1. Exploring Substrate Scope of Shi-Type Epoxidations.
- Author
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Nieto, Natalia, Munslow, Ian J., Fern�ndez-P�rez, H�ctor, and Vidal-Ferran, Anton
- Subjects
- *
BIOCHEMICAL substrates , *EPOXIDATION , *ENANTIOSELECTIVE catalysis , *HYDRATES , *CHEMICAL yield , *CHEMICAL derivatives , *STYRENE - Abstract
Enantioselective epoxidations of alkenes (12 examples) were achieved using a Shi-type carbohydrate-derived hydrate and Oxone. The chiral platform provided by the catalyst tolerates a wide range of substituents providing high yields and enantioselectivities (80-95.5% ee). However, styrene derivatives were only converted with poor selectivities (11-26% ee). [ABSTRACT FROM AUTHOR]
- Published
- 2008
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