1. Description of fourteen new DRB alleles found in a stem cell donor registry.
- Author
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Tang TF, Lin YS, Robbins FM, Li L, Sintasath D, Coquillard G, Huang A, Heine U, Ng J, Hartzman RJ, and Hurley CK
- Subjects
- HLA-DRB1 Chains, HLA-DRB3 Chains, HLA-DRB5 Chains, Humans, Registries, Sequence Analysis, DNA, Tissue Donors, Alleles, HLA-DR Antigens genetics, Stem Cells
- Abstract
Fourteen DRB alleles, DRB1*0705, DRB1*11014, DRB1*1134, DRB1*1136, DRB1*1141, DRB1*1335, DRB1*1337, DRB1*1338, DRB1*1342, DRB1*1343, DRB1*1349, DRB1*1510, DRB3*0105, and DRB5*0103, are described. Among them, eleven are variants which differ by only one nucleotide from previously described alleles, including one silent variant (DRB1*11014). Alleles, DRB1*0705, DRB1*1335 and DRB3*0105, display unique sequence motifs that have never been observed in DRB alleles.
- Published
- 2002
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