1. Respiratory allergies with no associated food allergy disrupt oral mucosa integrity.
- Author
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Sanchez‐Solares, Javier, Delgado‐Dolset, Maria I., Mera‐Berriatua, Leticia, Hormias‐Martin, Gonzalo, Cumplido, Jose A., Saiz, Vanesa, Carrillo, Teresa, Moreno‐Aguilar, Carmen, Escribese, Maria M., Gomez‐Casado, Cristina, and Barber, Domingo
- Subjects
ORAL mucosa ,RESPIRATORY allergy ,FOOD allergy ,ALLERGIC conjunctivitis - Abstract
Numbers of langerin+ cells among the experimental groups were similar; however, Fc RI expression in these cells tended to be higher in the oral epithelium of allergic patients (data not shown). To our knowledge, this is the first study describing an affected oral mucosa in the absence of food allergy and opens new ways of understanding barrier alterations associated with respiratory allergy. A disrupted barrier could be responsible for the progression to food allergy when the affected oral mucosa gets in direct contact with a trigger.[2] In fact, many food allergies are associated with previous respiratory sensitizations (PR10, lipid transfer proteins, profilins).[10]. [Extracted from the article]
- Published
- 2019
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