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Objective: To explore factors that influence the introduction of role extension in radiography and to discuss its potential for improved healthcare in Ghana., Key Findings: Key findings of this review are the lack of literature on role extension in radiography in Ghana. The factors that have influenced the introduction of role extension in radiography globally include a shortage of radiologists, increased demand for radiology services, government policy and radiographer's desire for professional development., Conclusions: Evidence indicates that radiographers can report radiographs as accurately as radiologists and appropriate education improves their performance. Radiographer-led reporting is the professional practise most likely to deliver local patient benefit. Developments in professional perceptions, training, education and regulation of reporting are required to establish confidence in radiography-led reporting., Implications for Practice: Radiographer reporting has the potential to improve patient outcomes, reduce waiting times, increase job satisfaction for radiographers and result in financial savings., (Copyright © 2019 The College of Radiographers. Published by Elsevier Ltd. All rights reserved.)