1. Association of hemoglobin values at booking with adverse maternal outcomes among Peruvian populations living at different altitudes.
- Author
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Gonzales GF, Tapia V, Gasco M, Carrillo CE, and Fort AL
- Subjects
- Adult, Anemia epidemiology, Anemia etiology, Cohort Studies, Databases, Factual, Female, Fetal Membranes, Premature Rupture epidemiology, Fetal Membranes, Premature Rupture etiology, Humans, Maternal Mortality, Peru epidemiology, Postpartum Hemorrhage epidemiology, Postpartum Hemorrhage etiology, Pre-Eclampsia epidemiology, Pre-Eclampsia etiology, Pregnancy, Retrospective Studies, Risk Factors, Young Adult, Altitude, Hemoglobins metabolism, Pregnancy Outcome epidemiology
- Abstract
Objective: To determine hemoglobin values associated with adverse maternal outcomes among Peruvian populations at different altitudes., Methods: A retrospective cohort study was conducted using data from the Perinatal Information System. Adverse maternal outcomes were assessed., Results: Risk of pre-eclampsia increased at maternal hemoglobin levels above 14.5 g/dL (OR 1.27; 95% CI, 1.18-1.36) or below 7.0 g/dL (OR 1.52; CI 95%, 1.08-2.14). Altitude above 2000 m reduced risk (OR 0.65; 95% CI 0.62-0.68). Risk of postpartum hemorrhage (PPH) increased with moderate/severe anemia (OR 6.15; 95% CI, 3.86-9.78) and at moderate altitudes (OR 1.26; 95% CI, 1.12-1.43). Mild anemia at any altitude was associated with reduced risk of pre-eclampsia (OR 0.85, 95% CI, 0.81-0.89) and PPH (OR 1.01; 95% CI, 0.88-1.15). Risk of premature rupture of membranes was reduced at high hemoglobin values. Maternal mortality increased at hemoglobin levels below 9.0 g/dL (OR 5.68; 95% CI, 2.97-10.80) and above 14.5 g/dL (OR 2.18; 95% CI, 1.22-3.91). Maternal mortality increased at moderate altitudes (OR 29.2; 95% CI, 2.62-324.60) and high altitudes (OR 66.4; 95% CI, 6.65-780.30) when hemoglobin levels were below 9.0 g/dL., Conclusion: Elevated altitude and hemoglobin levels influence maternal outcomes., (Copyright © 2012 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.)
- Published
- 2012
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