1. Onset of dialysis encephalopathy in cyclosporine-treated renal allograft recipients.
- Author
-
Hawley CM, Rigby RJ, Boyle RS, and Petrie JJ
- Subjects
- Adult, Aluminum analysis, Brain metabolism, Cyclosporins therapeutic use, Electroencephalography, Female, Humans, Male, Middle Aged, Renal Dialysis, Aluminum adverse effects, Cyclosporins adverse effects, Dementia chemically induced, Kidney Transplantation
- Abstract
Three patients who developed typical features of dialysis encephalopathy following renal transplantation are presented. No patient had evidence of overt neurological dysfunction pretransplantation. All patients were taking cyclosporine at the time of onset of neurological disease. Two patients died as a result of their neurological condition. The third patient made a satisfactory recovery. Factors responsible for the onset of dialysis encephalopathy in the renal posttransplantation period are discussed. We propose that cyclosporine may have been an important precipitating factor of the neurological syndrome of these patients.
- Published
- 1990
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