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AbstractIntroductionMaterials and methodsResultsDiscussionThe Latin American Spanish version of the Face-Name Associative Memory Exam (LAS-FNAME) has shown promise in identifying cognitive changes in those at risk for Alzheimer’s disease (AD). However, its applicability for Mild Cognitive Impairment (MCI) detection in the Latin American population remains unexplored. This study aims to analyze the psychometric properties in terms of validity and reliability and diagnostic performance of the LAS-FNAME for the detection of memory disorders in patients with amnestic MCI (aMCI).The study included 31 participants with aMCI, diagnosed by a neurologist according to Petersen’s criteria, and 19 healthy controls. Inclusion criteria for the aMCI group were to be 60 years of age or older, report cognitive complaints, have a memory test score (Craft Story 21) below a -1.5 z-score and have preserved functioning in activities of daily living. Participants completed LAS-FNAME and a comprehensive neuropsychological assessment.LAS-FNAME showed the ability to discriminate against healthy controls from patients with aMCI (AUC= 75) in comparison with a gold-standard memory test (AUC = 69.1). LAS-FNAME also showed evidence of concurrent and divergent validity with a standard memory test (RAVLT) (r = 0.58, p < .001) and with an attention task (Digit Span) (r = −0.37, p = .06). Finally, the reliability index was very high (α = 0.88).LAS-FNAME effectively distinguished aMCI patients from healthy controls, suggesting its potential for detecting early cognitive changes in Alzheimer’s prodromal stages among Spanish speakers. [ABSTRACT FROM AUTHOR]

Introduction. The "7- Minute Screen" is a neurocognitive screening test for the detection of Alzheimer's disease (AD) patients in primary care settings. It consists of 4 brief subtests (orientation, memory, visuoconstruction and verbal fluency) and provides a broader neuropsychological profile than other widely used screening tests. The aim of the present study was to study the usefulness of this screening test for the detection of Mild Cognitive Impairment (MCI). Methods. Thirty-two patients with probable AD (NINCDS-ADRDA criteria), 25 patients with MCI, and 35 healthy control subjects, matched for age and education, underwent a comprehensive neuropsychological battery and the Rio-de-la-Plata version of the 7-Minute Screen. Results. This test showed 93 % sensitivity and 97 % specificity in detecting mild-moderate Alzheimer's disease MMSE < 24), but it exhibited a substantially decreased sensitivity (28 %) in its ability to detect MCI in AD (MMSE >24). Conclusion. The screening batteries do not replace a more comprehensive neuro psychological assessment. They are useful in detecting patients with mild dementia, but caution must be the rule when considering a diagnosis of MCL. [ABSTRACT FROM AUTHOR]