1. Frontotemporal dementia phenotype in late-onset Huntington disease without chorea.
- Author
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Bonato, Giulia, Mozzetta, Stefano, Bussè, Cinzia, Cecchin, Diego, and Cagnin, Annachiara
- Subjects
FRONTOTEMPORAL dementia ,HUNTINGTON disease ,MOVEMENT disorders ,ALZHEIMER'S disease ,SPINOCEREBELLAR ataxia ,CHOREA ,MILD cognitive impairment - Abstract
Although brain amyloidosis was detected with CSF biomarker, a diagnosis of co-morbid Alzheimer disease was excluded due to negative biomarkers of amyloid-related neurodegeneration. In fact, the diagnosis of probable bvFTD requires functional imaging in cases where brain CT/MRI does not reveal atrophic changes in frontal and/or temporal lobes [[7]]. 1[ 18 F]FDG-PET/MRI of the brain of the patient detailing mild hypometabolism in the bilateral fronto-mesial cortex and involvement of the caudate nucleus bilaterally, which appears hypometabolic compared to the putamen. [Extracted from the article]
- Published
- 2023
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