1. ATP5H/KCTD2 locus is associated with Alzheimer's disease risk
- Author
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Boada, Mercè, Antúnez, Carmen, Ramírez Lorca, Repo, DeStefano, Anita L., González Pérez, A., Gayán, Javier, López Arrieta, Jesús, Ikram, M. Arfan, Hernández, Isabel, Marín, J., Galán, José Jorge, Bis, Joshua C., Mauleón, Ana, Rosende-Roca, Maitée, Moreno Rey, Concha, Gudnason, Vilmundur, Morón, Francisco Jesús, Velasco, Juan, Carrasco, José Miguel, Alegret, Montserrat, Espinosa, Ana, Vinyes, Georgina, Lafuente, Asunción, Vargas, Liliana, Fitzpatrick, Annette L., Launer, Lenore Joy, Sáez, María Eugenia, Vázquez, Enrique, Becker, James T., López, Oscar L., Serrano Ríos, Manuel, Tárraga, Lluís, van Duijn, Cornelia M., Real, Luis M., Seshadri, Sudha, Ruiz, Agustín, Universitat Autònoma de Barcelona, Radiology & Nuclear Medicine, and Epidemiology
- Subjects
Male ,Genotyping Techniques ,SNP ,Locus (genetics) ,Genome-wide association study ,Biology ,Polymorphism, Single Nucleotide ,molecular epidemiology ,Cohort Studies ,Cellular and Molecular Neuroscience ,Alzheimer Disease ,medicine ,genomics ,Humans ,GWAS ,Computer Simulation ,Genetic Predisposition to Disease ,Molecular Biology ,Genotyping ,Genetic association ,Genetics ,Aged, 80 and over ,Odds ratio ,Genomics ,Middle Aged ,Alzheimer's disease ,medicine.disease ,3. Good health ,Psychiatry and Mental health ,Genetic Loci ,Molecular epidemiology ,Female ,Original Article ,Mitochondrial ADP, ATP Translocases ,Genome-Wide Association Study - Abstract
To identify loci associated with Alzheimer disease, we conducted a three-stage analysis using existing genome-wide association studies (GWAS) and genotyping in a new sample. In Stage I, all suggestive single-nucleotide polymorphisms (at P
- Published
- 2014