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1. Synthesis and enantiomeric resolution of (±)-pinocembrin.

Author

Yuan, Yue, Yang, Qing-Yun, Tong, Yuan-Feng, Chen, Feng, Qi, Yan, Duan, Ya-Bo, and Wu, Song

Subjects
AMINES, ENANTIOMERS, ORGANIC compounds, TARTARIC acid, DIASTEREOISOMERS, OPTICAL isomers
Abstract

A convenient method for the synthesis and enantiomeric resolution of ( ± )-pinocembrin has been developed. This route involves the hydrogenation of 5,7-dihydroxyflavone, the derivatization of racemic pinocembrin with chiral amine, and the separation of the diastereoisomers due to their different physical properties. [ABSTRACT FROM AUTHOR]

Published
2008
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