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Novel 2,3-dihydro-4-pyridinones were synthesized via the reaction of curcumin and primary amines or amine acetates under microwave irradiation. Montmorillonite K-10 was used as a catalyst. Reaction times did not exceed 120 s. The structures of the compounds were established by elemental analysis and from their mass, ¹H- and 13C-NMR spectra. [ABSTRACT FROM AUTHOR]

Symmetrical and non-symmetrical diimines derived from dimedone were synthesized by the reaction of their corresponding enaminothiones with primary amines. The synthesized compounds were characterized using micro analytical data and NMR spectroscopy. Theoretical calculations by B3LYP/6-31G(d,p) level of theory show that the enolic form is the most stable within the possible tautomeric forms of the compounds. [ABSTRACT FROM AUTHOR]

¹H and 13C NMR spectra of dihydropyridones derived from curcumin were discussed and their structures were elucidated accordingly. Both one dimensional, HOMO- and HETERO-COSY spectra were used in this study. Computational calculations using B3LYP/6-311G(d,p) level of theory were undertaken to predict the structural properties of one molecule. The optimized structure was then used to calculate the NMR chemical shifts at the B3LYP/6-311G(d,p) level using the GIAO method. The calculated ¹H and 13C chemical shifts were compared with the experimental data. The calculated chemical shifts are in compliance with the experimental findings. [ABSTRACT FROM AUTHOR]

Abstract: A novel synthesis of 2,3-dihydro-4-pyridinones via the reaction of bisdemethoxycurcumin and primary amines or amine acetates is demonstrated. The structures of the products were established by elemental analysis and from mass, 1H and 13C NMR spectra. [Copyright &y& Elsevier]

Abstract: Dihydropyridones were prepared by microwave-assisted reaction between curcumin and primary amines or their acetates in the presence of Montmorillonite (K-10) as a catalyst. The reaction was complete within a few minutes and the yield depends on the amine used. [Copyright &y& Elsevier]