1. Discordance in Mycobacterium tuberculosis Rifampin Susceptibility.
- Author
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Kalokhe, Ameeta S., Shafiq, Majid, Lee, James C., Metchock, Beverly, Posey, James E., Ray, Susan M., Anderson, Albert, Wang, Yun F., and Nguyen, Minh Ly T.
- Subjects
HOMELESS women ,AIDS patients ,TUBERCULOSIS ,DRUG resistance in microorganisms ,ISONIAZID ,RIFAMPIN ,ANTITUBERCULAR agents ,SYMPTOMS ,MYCOBACTERIUM tuberculosis ,AMINOGLYCOSIDES - Abstract
The article discusses the case of a 45-year-old homeless woman with acquired immune deficiency syndrome (AIDS) who experienced pulmonary tuberculosis (TB) relapse with an associated resistance to antituberculous drugs isoniazid (INH) and rifampin (RIF). Her symptoms included fever, night sweats, weight loss and cough. She tested positive for Mycobacterium tuberculosis complex in August 2009, while the culture of the sputum specimen obtained at her admission indicated that the isolate was resistant to INH but susceptible to RIF. After a week, mycobacteriology laboratory findings showed that the isolate was resistant to both INH and RIF. The patient underwent injectable aminoglycoside therapy following her readmission.
- Published
- 2012
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