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1. Amygdala reactivity to emotional faces at high and low intensity in generalized social phobia: a 4-Tesla functional MRI study.

Author

Yoon KL, Fitzgerald DA, Angstadt M, McCarron RA, and Phan KL

Subjects
Adult, Arousal physiology, Cues, Dominance, Cerebral physiology, Female, Humans, Limbic System physiopathology, Male, Phobic Disorders diagnosis, Amygdala physiopathology, Emotions physiology, Facial Expression, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Phobic Disorders physiopathology
Abstract

Using functional magnetic resonance imaging, we measured amygdala reactivity to faces varying on emotional intensity in subjects with generalized social phobia (GSP) and matched healthy controls, and observed greater bilateral activation to high (vs. low) intensity expressions in the phobic group, suggesting that more arousing social-emotional cues contribute to limbic hyperactivity in GSP.

Published
2007
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