1. Developmental neuron cell death in dystrophic and normal chickens
- Author
-
Barnett Richard Irwin
- Subjects
Motor Neurons ,animal structures ,Cell Survival ,Dystrophic muscle ,Embryo ,Cell Count ,Anatomy ,Chick Embryo ,Growth ,Biology ,Chick embryos ,Embryonic stem cell ,Cell loss ,Muscular Dystrophies ,Andrology ,Developmental Neuroscience ,Neurology ,Spinal Cord ,embryonic structures ,Nerve Degeneration ,Animals ,Neuron cell death ,Chickens - Abstract
The numbers of motoneurons in the brachial lateral motor columns were determined from the 6th embryonic day through the 5th week posthatching in age-matched dystrophic and normal chickens. The overall magnitude of cell loss was not significantly different between the dystrophic and normal strains. However there was a trend toward more motoneurons in the brachial lateral motor columns of dystrophic embryos and posthatch chickens which was found to be statistically significant at the 8th and 9th days of embryonic life. These observations are taken to suggest that, in addition to strain differences unrelated to the dystrophic gene, there may exist a temporal delay in developmental neuron cell death in dystrophic chick embryos that may be secondary to the primary defect within the dystrophic muscle.
- Published
- 1985