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1. Second-Generation Tyrosine Kinase Inhibitors in the Post-Transplant Period in Patients with Chronic Myeloid Leukemia or Philadelphia-Positive Acute Lymphoblastic Leukemia.

Author

Klyuchnikov, Evgeny, Schafhausen, Philippe, Kröger, Nicolaus, Brummendorf, Tim H., Osanmaz, Okay, Asenova, Svetlana, Zabelina, Tatjana, Ocheni, Sunday, Ayuk, Francis, Zander, Axel R., and Bacher, Ulrike

Subjects
CLINICAL trials, MYELOID leukemia, LYMPHOBLASTIC leukemia, PROTEIN-tyrosine kinases, ANEMIA
Abstract

The article describes the clinical outcome of 11 patients, particularly nine patients with chronic myeloid leukemia (CML) and two patients with Philadelphia-positive acute lymphoblastic leukemia (Phi+ ALL), who received second-generation tyrosine kinase inhibitor (TKI) treatment in the post-transplant period. The preliminary findings show that application of second generation tyrosine kinase inhibitors is feasible in the post-transplant period. The researchers note that tolerance might be comparable with the application in a standard treatment scenario.

Published
2009
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