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Start Over Author "Dufour, Marine" Topic anilides
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1. One-pot and regiospecific synthesis of 2,3-disubstituted indoles from 2-bromoanilides via consecutive palladium-catalyzed Sonogashira coupling, amidopalladation, and reductive elimination.

Author

Lu BZ, Wei HX, Zhang Y, Zhao W, Dufour M, Li G, Farina V, and Senanayake CH

Subjects
Catalysis, Cyclization, Indoles chemistry, Molecular Structure, Organometallic Compounds chemistry, Oxidation-Reduction, Amides chemistry, Anilides chemistry, Hydrocarbons, Brominated chemistry, Indoles chemical synthesis, Palladium chemistry
Abstract

A practical one-pot and regiospecific three-component process for the synthesis of 2,3-disubstituted indoles from 2-bromoanilides was developed via consecutive palladium-catalyzed Sonogashira coupling, amidopalladation, and reductive elimination.

Published
2013
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