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Factors such as growth in human and livestock populations, climate change, and the globalization of trade are creating favourable conditions for the emergence of new and more complex public health threats. One Health (sometimes referred to as One World One Health) is an approach that considers complex public health threats through an integrated lens of animal, human and ecosystem health. Within the last five years, the One Health approach has been gaining momentum in the international and national community. This paper will focus on human population growth, food and water security and climate change as three factors that have a major influence on the emergence or re-emergence of disease and highlight the importance of facilitating understanding, integration and collaboration between the different sectors. [ABSTRACT FROM PUBLISHER]