1. Molecular characterization of Schistosoma infections in African migrants: identification of a Schistosoma haematobium-bovis hybrid in bladder biopsies.
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Marascio, Nadia, Loria, Maria Teresa, Lamberti, Angelo Giuseppe, Pavia, Grazia, Adams, Neill James, Quirino, Angela, Divenuto, Francesca, Mazzitelli, Maria, Greco, Giuseppe, Trecarichi, Enrico Maria, Perandin, Francesca, Bisoffi, Zeno, Webster, Bonnie L, Liberto, Maria Carla, Torti, Carlo, and Matera, Giovanni
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SCHISTOSOMIASIS diagnosis ,AFRICANS ,NOMADS ,BLADDER ,TREMATODA ,BIOPSY ,ANIMALS - Abstract
The I S. haematobium cox1 i data from all samples matched the common H1 haplotypes found across mainland Africa.[7] The I cox1 i data from the bladder biopsy identified both I S. bovis i and I S. haematobium i mitochondrial DNA. Keywords: ITS2; cox1; Schistosoma hybrid; phylogenetic analysis EN ITS2 cox1 Schistosoma hybrid phylogenetic analysis 1 3 3 11/09/22 20221001 NES 221001 Schistosomiasis is a neglected tropical disease affecting up to 90% of people living in Africa.[1] The emergence of natural inter I Schistosoma i species hybrids clearly highlights potential risks of mixing between human and animal infections, enhancing transmission and the spread of new strains.[2] In particular, I Schistosoma haematobium i and I Schistosoma bovis i are closely related, are known to hybridize and also share snail intermediate hosts of the genus I Bulinus i .[3] The I S. haematobium-bovis i hybrid diagnosis in patients plays an important role in explaining unusual morbidities and disease outcomes together with the potential risk of introduction into non-endemic areas I . i [2],[4] Herein, to identify the potential presence of I S. haematobium-bovis i hybrids, we molecularly characterized typical and atypical eggs, presumed to be I S. haematobium i , collected from young African migrants. [Extracted from the article]
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- 2022
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