1. Vaccination With
- Author
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Reetika, Chaurasia, Aryeh, Salovey, Xiaojia, Guo, Gary, Desir, and Joseph M, Vinetz
- Subjects
Leptospira ,Mice, Inbred C3H ,Virulence ,Escherichia coli Proteins ,Vaccination ,Kidney ,Bacterial Load ,Recombinant Proteins ,Mice ,Liver ,Bacterial Vaccines ,Escherichia coli ,Animals ,Humans ,Leptospirosis ,Leptospira interrogans - Abstract
The molecular and cellular pathogenesis of leptospirosis remains poorly understood. Based on comparative bacterial genomics data, we recently identified the hypothetical PF07598 gene family as encoding secreted exotoxins (VM proteins) that mediate cytotoxicity
- Published
- 2022