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28 results on '"M S, Lomakin"'

1. [Types of cellular antitumor cytotoxicity]

Author

M S, Lomakin and I N, Maĭskiĭ

Subjects
Cytotoxicity, Immunologic, Killer Cells, Natural, Immunity, Cellular, Neoplasms, Antibody-Dependent Cell Cytotoxicity, Tumor Cells, Cultured, Animals, Humans, Neoplasms, Experimental, Lymphocyte Culture Test, Mixed, Lymphocyte Activation, Immunologic Surveillance, T-Lymphocytes, Cytotoxic
Published
1988

4. [A blocking factor in normal animal sera inhibiting immunologic reactions in vitro]

Author

M S, Lomakin, V L, Levetina, and A S, Larin

Subjects
Antigen-Antibody Reactions, Male, Chemistry, Hot Temperature, Chemical Phenomena, Immune Sera, Age Factors, Animals, Female, Rats
Abstract

An extremely thermostable and resistant to some chemical substances factor was found in the sera of Wistar and noninbred rats of different age, male and female. This factor inhibited the action of normal and immune antibodies to rat erythrocytes and rat serum antigens. The blocking factor was relatively specific and more effective in respect to the normal antibodies than to the immune ones. The activity of the blocking factor was connected with the alpha1-globulin.

Published
1975

5. [Immunologic responses of the body to tumors induced by DMBA]

Author

M S, Lomakin, I N, Maĭskiĭ, A S, Larin, and V L, Levitina

Subjects
Immunity, Cellular, 9,10-Dimethyl-1,2-benzanthracene, Macrophages, Transplantation, Autologous, Rats, Cell Movement, Agglutination Tests, Cell Migration Inhibition, Rhabdomyosarcoma, Benz(a)Anthracenes, Animals, Ascitic Fluid, Sarcoma, Experimental, Neoplasm Transplantation
Abstract

As a result of the complex immunobiological study in an autologous system on the models of DMBA induced tumors in muscular tissue there were shown 3 types of cell response to primary tumors, their metastases and autotransplantation: no response, moderate and very pronounced reaction. In a definite percentage of cases autologous peritoneal macrophages were found to inhibit malignant cells in autotransplantation. The percentage of positive inoculations and an average weight of transplants of primary tumors and their metastases at the moment of highest transplantation immunity (12-14 days) have been definitely correlated with the intensity of cell response developed in these tissue, and also are dependent on individual features of proper malignant cells.

Published
1975

6. [Factors of bodily resistance and metastasis]

Author

I N, Maĭskiĭ and M S, Lomakin

Subjects
Immunity, Cellular, Immune Sera, Neoplasms, Experimental, Transplantation, Autologous, Rats, Cortisone, Mice, Radiation Injuries, Experimental, Antigens, Neoplasm, Neoplasm Regression, Spontaneous, Lymphatic Metastasis, Neoplasms, BCG Vaccine, Carcinogens, Animals, Humans, Transplantation, Homologous, Immunization, Lymph Nodes, Neoplasm Metastasis, Neoplasm Transplantation
Published
1976

7. [Thermo-stable tumor-associated antigens in the serum of tumor-bearing animals and in tissue cultures of malignant tumors]

Author

M S, Lomakin, A S, Larin, and I N, Maĭskiĭ

Subjects
Male, Immunodiffusion, Antigens, Neoplasm, Chinchilla, 9,10-Dimethyl-1,2-benzanthracene, Animals, Female, Neoplasms, Experimental, Rabbits, Immunoelectrophoresis
Abstract

Gel precipitation and immunoelectrophoresis have demonstrated the presence of thermostable tumour-associated antigens in blood serum from tumour-bearing rats and culture supernatant of malignant cells. These antigens have the electrophoretic mobility in the zones of beta-, alpha- and alpha 1-globulins.

Published
1980

8. [Antigens common to Mycobacterium bovis (BTsZh) and several malignant and normal tissues of laboratory animals]

Author

M S, Lomakin, I N, Maĭskiĭ, T N, Mamaeva, A S, Larin, and V L, Levitina

Subjects
Immunodiffusion, Erythrocytes, Muscles, Mammary Neoplasms, Experimental, Neoplasms, Experimental, Mycobacterium bovis, Rats, Liver, Agglutination Tests, Antigens, Heterophile, Animals, Adenofibroma, Immunoelectrophoresis, Spleen
Abstract

Agglutination, gel precipitation and immunoelectrophoresis tests demonstrated the presence of antigens common for the Mycobacterium bovis (BCG) and some malignant and normal rat tissue cells. The method of absorption of immune sera in the agglutination test showed that this antigen was specific for the BCG microorganisms and cells of primary induced tumours of rat muscle tissue. This antigen had the electrophoretic mobility in the beta-globulin zone.

Published
1977

9. [Thermostable antigens of malignant tumors and normal tissues of experimental animals]

Author

M S, Lomakin, A S, Larin, and I N, Maĭskiĭ

Subjects
Male, Epitopes, Immunodiffusion, Hot Temperature, Organ Specificity, 9,10-Dimethyl-1,2-benzanthracene, Animals, Female, Neoplasms, Experimental, Rabbits, Antigens, Immunoelectrophoresis, Rats
Abstract

Gel precipitation and immunoelectrophoresis tests tests demonstrated the presence of thermostable antigens in dimethylbenzanthracene-induced malignant tumours of the muscle tissues of Wistar rats. These antigens were relatively tissue-specific for the tumours, amniotic fluid and the uterus on the one hand, and for the lung, spleen, and the serum on the other hand. The thermostable antigens of the tumours and the amniotic fluid had the electrophoretic mobility in the zone of alpha and alpha1-globulins.

Published
1978

10. [Serum factors that inhibit in vitro immunological reactions in malignant tumor development in experimental animals]

Author

M S, Lomakin, A S, Larin, T N, Mamaeva, and V L, Levitina

Subjects
Immunosuppression Therapy, Mice, Inbred C3H, Carcinoma, Hepatocellular, Time Factors, Immune Sera, Macrophages, Liver Neoplasms, Antigen-Antibody Complex, Neoplasms, Experimental, In Vitro Techniques, Immune Adherence Reaction, Rats, Antigen-Antibody Reactions, Mice, Animals, Female, Lymphocytes, Neoplasm Transplantation
Abstract

In two immunological reactions (immunocytoadherence and inhibition of macrophage adherence in the presence of specific antigens) it was shown that autologous and homologous native sera in some percentage of cases render an inhibitory effect. One of the blocking factors of sera proved to be rather thermostable, the other, on the contrary, to be thermolable.

Published
1977

13. [Metastasization or 'RA' rat kidney carcinoma]

Author

M S, Lomakin and Iu S, Krivoshein

Subjects
Male, Lymphatic Metastasis, Splenic Neoplasms, Liver Neoplasms, Animals, Seminal Vesicles, Neoplasms, Experimental, Neoplasm Metastasis, Kidney Neoplasms, Neoplasm Transplantation, Rats
Published
1965

15. [Several properties of the serum factor from normal animals and animals with tumors in the gel precipitation reaction]

Author

M S, Lomakin and T A, Pokrovskaia

Subjects
Immunodiffusion, Carcinoma, Hepatocellular, Tissue Extracts, Lymphoma, Non-Hodgkin, Muscles, Guinea Pigs, Liver Neoplasms, Mammary Neoplasms, Experimental, Sarcoma, Neoplasms, Experimental, Kidney, Rats, Mice, Neoplasms, Muscle Tissue, Blood, Mammary Glands, Animal, Liver, Neoplasms, Animals, Rabbits, Adenofibroma, Immunoelectrophoresis
Published
1969

23. [On immunobiological mechanisms of metastasis of malignant tumors]

Author

I N, Maĭskiĭ, M S, Lomakin, and Iu S, Krivoshein

Subjects
Electrophysiology, Mice, Radiotherapy, Cell Wall, Animals, Hyaluronoglucosaminidase, Hemorrhage, Rabbits, Antigens, Neoplasm Metastasis, Gonadal Steroid Hormones, Mononuclear Phagocyte System, Hormones
Published
1967

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