1. The modeled cost-effectiveness of family-based and adolescent-focused treatment for anorexia nervosa.
- Author
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Le LK, Barendregt JJ, Hay P, Sawyer SM, Hughes EK, and Mihalopoulos C
- Subjects
- Adolescent, Anorexia Nervosa therapy, Child, Female, Humans, Male, Anorexia Nervosa economics, Cost-Benefit Analysis methods
- Abstract
Background: Anorexia nervosa (AN) is a prevalent, serious mental disorder. We aimed to evaluate the cost-effectiveness of family-based treatment (FBT) compared to adolescent-focused individual therapy (AFT) or no intervention within the Australian healthcare system., Method: A Markov model was developed to estimate the cost and disability-adjusted life-year (DALY) averted of FBT relative to comparators over 6 years from the health system perspective. The target population was 11-18 year olds with AN of relatively short duration. Uncertainty and sensitivity analyses were conducted to test model assumptions. Results are reported as incremental cost-effectiveness ratios (ICER) in 2013 Australian dollars per DALY averted., Results: FBT was less costly than AFT. Relative to no intervention, the mean ICER of FBT and AFT was $5,089 (95% uncertainty interval (UI): dominant to $16,659) and $51,897 ($21,591 to $1,712,491) per DALY averted. FBT and AFT are 100% and 45% likely to be cost-effective, respectively, at a threshold of AUD$50,000 per DALY averted. Sensitivity analyses indicated that excluding hospital costs led to increases in the ICERs but the conclusion of the study did not change., Conclusion: FBT is the most cost-effective among treatment arms, whereas AFT was not cost-effective compared to no intervention. Further research is required to verify this result., (© 2017 Wiley Periodicals, Inc.)
- Published
- 2017
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