1. Ultrasonographic and biochemical assessments as early prediction of polycystic ovarian syndrome in obese women
- Author
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Maryam A Alghamdi, Alaa A Ahmed, Taha A. Kumosani, Said S Moselhy, Etimad A. Huwait, Majdi H AlToukhi, Afnan T Kumosani, and Khalid A Al-Madani
- Subjects
Adult ,endocrine system diseases ,medicine.medical_treatment ,030231 tropical medicine ,Dehydroepiandrosterone ,Physiology ,Body Mass Index ,Anovulation ,03 medical and health sciences ,0302 clinical medicine ,Ultrasound ,Diagnosis ,PCOS ,medicine ,Humans ,Insulin ,Testosterone ,Obesity ,hormones ,business.industry ,Ovary ,Hyperandrogenism ,nutritional and metabolic diseases ,Articles ,General Medicine ,medicine.disease ,Polycystic ovary ,female genital diseases and pregnancy complications ,Case-Control Studies ,Female ,Follicle Stimulating Hormone ,business ,Polycystic Ovary Syndrome ,Hormone - Abstract
Backgroud: Polycystic ovary syndrome (PCOS) is considered as a common cause of hormonal disturbance and obesity. The diagnosis of PCOS was done by different methods including clinical signs as anovulation, hyperandrogenism, biochem- ical markers and ultrasounographic investigation. This study investigated comparative outcomes of ultrasonographic and biochemical markers for early prediction of PCOS in obese women. Subjects and methods: Seventy-five patients were clinically diagnosed with obese, PCOS and obese with PCOS and twen- ty-five normal age matched subjects were enrolled as control. Abdominal and transvaginal ultrasonographic for assessment of ovarian properties. In addition, BMI, serum free testosterone, dehydroepiandrosterone (DHEA), insulin, glycosylated hemoglobin (HbA1c) and LDL-c levels were evaluated. Results: In obese patients with PCOs (20%) ovaries revealed normal appearance in morphology while the rest (80%) showed PCOs in the form of cysts of 2–8 mm in diameter peripherally arranged around stroma. A significant elevation of free testosterone, DHEA and insulin in obese with or without PCOS compared with obese group (p
- Published
- 2020
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