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Change of direction manoeuvres is important in soccer and associated with non-contact anterior cruciate ligament injury, yet it is not known how the mechanics differentiate between males and females during 180° turns. Twenty-eight soccer players (14 males and 14 females) performed 180° turns with ground reaction forces collected over penultimate and final contacts. A two-way (contact × limb) multivariate analysis of variance (MANOVA) were run to examine differences between contact (penultimate and final) or limb (dominant and non-dominant) for sagittal plane hip, knee and ankle peak angles and moments, and frontal plane knee abduction moments and angles between sexes. Average horizontal GRF was increased on the dominant limb, compared to non-dominant and for the final contact compared to the penultimate contact. Knee abduction angles were increased in females compared to males, while the opposite was true for knee abduction moments. Statistically significant differences were evident, with increases in peak vertical GRF, peak hip flexion angle, peak knee flexion angle, peak knee extensor moment, and peak ankle dorsiflexion angle observed in the penultimate contact compared to final contact. The results indicate the penultimate contact during turns helps reduce loading on the final contact, yet male and female soccer players exhibit different knee joint mechanics during pre-planned change of direction.

Background: Eumenorrheic women experience cyclic variations in sex hormones attributed to the menstrual cycle (MC) which can impact anterior cruciate ligament (ACL) properties, knee laxity, and neuromuscular function. This systematic review aimed to examine the effects of the MC on ACL neuromuscular and biomechanical injury risk surrogates during dynamic tasks, to establish whether a particular MC phase predisposes women to greater ACL injury risk., Methods: PubMed, Medline, SPORTDiscus, and Web of Science were searched (May-July 2021) for studies that investigated the effects of the MC on ACL neuromuscular and biomechanical injury risk surrogates. Inclusion criteria were: 1) injury-free women (18-40 years); 2) verified MC phases via biochemical analysis and/or ovulation kits; 3) examined neuromuscular and/or biomechanical injury risk surrogates during dynamic tasks; 4) compared ≥1 outcome measure across ≥2 defined MC phases., Results: Seven of 418 articles were included. Four studies reported no significant differences in ACL injury risk surrogates between MC phases. Two studies showed evidence the mid-luteal phase may predispose women to greater risk of non-contact ACL injury. Three studies reported knee laxity fluctuated across the MC; two of which demonstrated MC attributed changes in knee laxity were associated with changes in knee joint loading (KJL). Study quality (Modified Downs and Black Checklist score: 7-9) and quality of evidence were low to very low (Grading of Recommendations Assessment Development and Evaluation: very low)., Conclusion: It is inconclusive whether a particular MC phase predisposes women to greater non-contact ACL injury risk based on neuromuscular and biomechanical surrogates. Practitioners should be cautious manipulating their physical preparation, injury mitigation, and screening practises based on current evidence. Although variable (i.e., magnitude and direction), MC attributed changes in knee laxity were associated with changes in potentially hazardous KJLs. Monitoring knee laxity could therefore be a viable strategy to infer possible ACL injury risk., Competing Interests: The authors have declared that no competing interests exist., (Copyright: © 2023 Dos’Santos et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)

Objectives: To investigate the relationship between the Landing Error Scoring System (LESS) and Cutting Movement Assessment Score (CMAS) to evaluate movement quality, their intra- (INTRAob) and inter-observer (INTERob) reliability, and the comparison between the two drop vertical jump (DVJ) landings (1st and 2nd)., Design: Cross-sectional., Participants: 42 male semi-professional soccer players performed three trials of DVJ and 70° change of direction with a ball located as an external focus., Main Outcome Measures: Movement quality was evaluated through 2D video footage using the CMAS and LESS, screened by two observers. Relational, comparative and reliability analyses were conducted., Results: Both tools showed moderate to substantial (ICC = 0.58-0.71), and substantial to almost perfect (ICC = 0.68-0.87) INTRAob and INTERob reliability, respectively. No significant associations were found among CMAS, LESS 1st and 2nd for either scores or risk profiles (r = -0.158-0.202, p > 0.05). LESS 2nd was moderately higher (ES = 0.80-0.83, p = 0.002-0.007) than 1st scores., Conclusions: CMAS and LESS are reliable tools to evaluate movement quality, although evaluations should be preferably performed by the same observer; ACL injury risk profile's is task-dependent; both landings of the DVJ should be assessed as they represent different biomechanical and neuromuscular control deficits., Competing Interests: Declaration of competing interest None., (Copyright © 2022 Elsevier Ltd. All rights reserved.)

Anterior cruciate ligament (ACL) is one of the most concerning injuries for football players. The aim of this review is to investigate the effects of exercise-based interventions targeting at reducing ACL injury rate or mitigating risk factors of ACL injury in adult football players. Following PRISMA guidelines, a systematic search was conducted in CINAHL, Cochrane Library, PubMed, Scopus, SPORTDiscus and Web of Science. Studies assessing the effect of exercise-based interventions in ACL injury incidence or modifiable risk factors in adult football players were included. 29 studies evaluating 4502 male and 1589 female players were included (15 RCT, 8 NRCT, 6 single-arm): 14 included warm-up, 7 resistance training, 4 mixed training, 3 balance, 1 core stability and 1 technique modification interventions. 6 out of 29 studies investigated the effect of interventions on ACL injury incidence, while the remaining 23 investigated their effect on risk factors. Only 21% and 13% studies evaluating risk of injury variables reported reliability measures and/or smallest worthwhile change data. Warm-up, core stability, balance and technique modification appear effective and feasible interventions to be included in football teams. However, the use of more ecologically valid tests and individually tailored interventions targeting specific ACL injury mechanisms are required.

The aim of this was study to examine the inter-task relationships and compare change of direction (COD) biomechanics between different angles (45°, 90°, and 180°). Twenty-seven men performed three COD tasks, whereby lower-limb and trunk kinematics and kinetics were assessed via 3D motion and ground reaction force (GRF) analysis. Key mechanical differences ( p ≤ 0.025, η 2  = 0.024-0.940) in velocity profiles, GRF, sagittal joint angles and moments, multiplanar knee joint moments, and technical parameters existed between CODs. The primary findings were that as COD angle increased, velocity profiles decreased ( p < 0.001, d = 1.56-8.96), ground contact times increased ( p < 0.001, d = 3.00-5.04), vertical GRF decreased ( p < 0.001, d = 0.87-3.48), and sagittal peak knee joint moments decreased ( p ≤ 0.040, d = 0.62-2.73). Notably, the greatest peak knee internal rotation (KIRMs) and abduction moments (KAMs) and angles were observed during the 90° COD ( p < 0.001, d = 0.88-1.81), indicating that this may be the riskiest COD angle. Small to very large ( r = 0.260-0.702) associations in KAMs and KIRMs were observed between tasks, indicating that evaluations at different angles are needed to develop an athlete's biomechanical injury risk profile. The results support the concept that COD biomechanics and potential surrogates of non-contact anterior cruciate ligament injury risk are "angle-dependent"; which have important implications for COD coaching, screening, and physical preparation.

Abstract: McBurnie, AJ, Dos'Santos, T, Jones, PA. Biomechanical associates of performance and knee joint loads during a 70-90° cutting maneuver in subelite soccer players. J Strength Cond Res 35(11): 3190-3198, 2021-The aim of this study was to explore the "performance-injury risk" conflict during cutting, by examining whole-body joint kinematics and kinetics that are responsible for faster change-of-direction (COD) performance of a cutting task in soccer players, and to determine whether these factors relate to peak external multiplanar knee moments. 34 male soccer players (age: 20 ± 3.2 years; body mass: 73.5 ± 9.2 kg; height: 1.77 ± 0.06 m) were recruited to investigate the relationships between COD kinetics and kinematics with performance and multiplanar knee joint moments during cutting. Three-dimensional motion data using 10 Qualisys Oqus 7 infrared cameras (240 Hz) and ground reaction force data from 2 AMTI force platforms (1,200 Hz) were collected to analyze the penultimate foot contact and final foot contact (FFC). Pearson's or Spearman's correlations coefficients revealed performance time (PT), peak external knee abduction moment (KAM), and peak external knee rotation moment (KRM) were all significantly related (p < 0.05) to horizontal approach velocity (PT: ρ = -0.579; peak KAM: ρ = 0.414; peak KRM: R = -0.568) and FFC peak hip flexor moment (PT: ρ = 0.418; peak KAM: ρ = -0.624; peak KRM: ρ = 0.517). Performance time was also significantly (p < 0.01) associated with horizontal exit velocity (ρ = -0.451) and, notably, multiplanar knee joint loading (peak KAM: ρ = -0.590; peak KRM: ρ = 0.525; peak KFM: ρ = -0.509). Cohen's d effect sizes (d) revealed that faster performers demonstrated significantly greater (p < 0.05; d = 1.1-1.7) multiplanar knee joint loading, as well as significantly greater (p < 0.05; d = 0.9-1.2) FFC peak hip flexor moments, PFC average horizontal GRFs, and peak knee adduction angles. To conclude, mechanics associated with faster cutting performance seem to be "at odds" with lower multiplanar knee joint loads. This highlights the potential performance-injury conflict present during cutting., (Copyright © 2019 National Strength and Conditioning Association.)

Background: Most cutting biomechanical studies investigate performance and knee joint load determinants independently. This is surprising because cutting is an important action linked to performance and non-contact anterior cruciate ligament (ACL) injuries. The aim of this study was to investigate the relationship between cutting biomechanics and cutting performance (completion time, ground contact time [GCT], exit velocity) and surrogates of non-contact ACL injury risk (knee abduction [KAM] and internal rotation [KIRM] moments) during 90° cutting., Design: Mixed, cross-sectional study following an associative design. 61 males from multidirectional sports performed six 90° pre-planned cutting trials, whereby lower-limb and trunk kinetics and kinematics were evaluated using three-dimensional (3D) motion and ground reaction force analysis over the penultimate (PFC) and final foot contact (FFC). Pearson's and Spearman's correlations were used to explore the relationships between biomechanical variables and cutting performance and injury risk variables. Stepwise regression analysis was also performed., Results: Faster cutting performance was associated (p ≤ 0.05) with greater centre of mass (COM) velocities at key instances of the cut (r or ρ = 0.533-0.752), greater peak and mean propulsive forces (r or ρ = 0.449-0.651), shorter FFC GCTs (r or ρ = 0.569-0.581), greater FFC and PFC braking forces (r = 0.430-0.551), smaller hip and knee flexion range of motion (r or ρ = 0.406-0.670), greater knee flexion moments (KFMs) (r = 0.482), and greater internal foot progression angles (r = - 0.411). Stepwise multiple regression analysis revealed that exit velocity, peak resultant propulsive force, PFC mean horizontal braking force, and initial foot progression angle together could explain 64% (r = 0.801, adjusted 61.6%, p = 0.048) of the variation in completion time. Greater peak KAMs were associated with greater COM velocities at key instances of the cut (r or ρ = - 0.491 to - 0.551), greater peak knee abduction angles (KAA) (r = - 0.468), and greater FFC braking forces (r = 0.434-0.497). Incidentally, faster completion times were associated with greater peak KAMs (r = - 0.412) and KIRMs (r = 0.539). Stepwise multiple regression analysis revealed that FFC mean vertical braking force and peak KAA together could explain 43% (r = 0.652, adjusted 40.6%, p < 0.001) of the variation peak KAM., Conclusion: Techniques and mechanics associated with faster cutting (i.e. faster COM velocities, greater FFC braking forces in short GCTs, greater KFMs, smaller hip and knee flexion, and greater internal foot progression angles) are in direct conflict with safer cutting mechanics (i.e. reduced knee joint loading, thus ACL injury risk), and support the "performance-injury conflict" concept during cutting. Practitioners should be conscious of this conflict when instructing cutting techniques to optimise performance while minimising knee joint loading, and should, therefore, ensure that their athletes have the physical capacity (i.e. neuromuscular control, co-contraction, and rapid force production) to tolerate and support the knee joint loading during cutting., (© 2021. The Author(s).)

Abstract: Dos'Santos, T, Thomas, C, Comfort, P, and Jones, PA. Biomechanical effects of a 6-week change-of-direction technique modification intervention on anterior cruciate ligament injury risk. J Strength Cond Res 35(8): 2133-2144, 2021-The aim of this study was to evaluate the biomechanical effects of a 6-week change-of-direction (COD) technique modification intervention on anterior cruciate ligament (ACL) injury risk (i.e., multiplanar knee joint loads) during 45° (CUT45) and 90° (CUT90) side-step cutting. A nonrandomized, controlled 6-week intervention study was administrated. Fifteen male multidirectional sport athletes formed the intervention group (IG) who participated in two 30-minute COD technique modification sessions per week, whereas 12 male multidirectional sport athletes formed the control group and continued their normal training. Subjects performed 6 trials of the CUT45 and CUT90 task whereby pre-to-post intervention changes in lower-limb and trunk kinetics and kinematics were evaluated using three-dimensional motion and ground reaction force analysis. Two-way mixed analyses of variance revealed no significant interaction effects of group for CUT45 and CUT90 multiplanar knee joint loads (p ≥ 0.116, η2 ≤ 0.096); however, considerable individual variation was observed (positive (n = 5-8) and negative responders (n = 7-8)). Based on IG group means, COD technique modification resulted in no meaningful reductions in multiplanar knee joint loads. However, individually, considerable variation was observed, with "higher-risk" subjects generally responding positively, and subjects initially considered "low-risk" tending to increase their multiplanar knee joint loads, albeit to magnitudes not considered hazardous or "high-risk." Change-of-direction technique modification training is a simple, effective training method, requiring minimal equipment that can reduce knee joint loads and potential ACL injury risk in "higher-risk" subjects without compromising performance., (Copyright © 2021 National Strength and Conditioning Association.)

Change of direction (COD) manoeuvres are associated with anterior cruciate ligament (ACL) injury risk due to the propensity to generate large multiplanar knee joint loads. Given the short- and long-term consequences of ACL injury, practitioners are interested in methods that reduce knee joint loads and subsequent ACL loading. An effective strategy to reduce ACL loading is modifying an athlete's movement mechanics to reduce knee joint loading. The purpose of this scoping review was to critically appraise and comprehensively synthesise the existing literature related to the effects of training interventions on COD biomechanics associated with increased knee joint loads and subsequent ACL loading, and identify gaps and recommend areas for future research. A review of the literature was conducted using Medline and Sport DISCUS databases. Inclusion criteria consisted of pre-post analysis of a COD task, a minimum 4-week training intervention, and assessments of biomechanical characteristics associated with increased ACL loading. Of the 1,027 articles identified, 22 were included in the scoping review. Based on current literature, balance training and COD technique modification are the most effective training modalities for reducing knee joint loading (small to moderate effect sizes). One study reported dynamic core stability training was effective in reducing knee joint loads, but further research is needed to definitively confirm the efficacy of this method. Perturbation-enhanced plyometric training, the F-MARC 11 + soccer specific warm-up, Oslo Neuromuscular warm-up, and resistance training are ineffective training modalities to reduce COD knee joint loads. Conflicting findings have been observed for the Core-Pac and mixed training programme. Consequently, practitioners should consider incorporating balance and COD technique modification drills into their athletes' training programmes to reduce potentially hazardous knee joint loads when changing direction. However, training intervention studies can be improved by investigating larger sample sizes (> 20), including a control group, acknowledging measurement error when interpreting their findings, and considering performance implications, to confirm the effectiveness of training interventions and improve adherence.

Objective: To assess the validity of the cutting movement assessment score (CMAS) to estimate the magnitude of peak knee abduction moments (KAM) against three-dimensional (3D) motion analysis, while comparing whole-body kinetics and kinematics between subjects of low (bottom 33%) and high CMASs (top 33%)., Design: Cross-sectional study., Setting: Laboratory., Participants: Forty-one participants (soccer, rugby, netball, and cricket)., Main Outcome Measures: Association between peak KAM and CMAS during a 90° cut. Comparison of 3D whole-body kinetics and kinematics between subjects with low (bottom 33%) and high CMASs (top 33%)., Results: A very large significant relationship (ρ = 0.796, p < 0.001) between CMAS and peak KAM was observed. Subjects with higher CMASs displayed higher-risk cutting postures, including greater peak knee abduction angles, internal foot progression angles, and lateral foot plant distances (p ≤ 0.032, effect size = 0.83-1.64). Additionally, greater cutting multiplanar knee joint loads (knee flexion, internal rotation, and abduction moments) were demonstrated by subjects with higher CMASs compared to lower (p ≤ 0.047, effect size = 0.77-2.24)., Conclusion: The CMAS is a valid qualitative screening tool for evaluating cutting movement quality and is therefore a potential method to identify athletes who generate high KAMs and "high-risk" side-step cutting mechanics., (Copyright © 2019 Elsevier Ltd. All rights reserved.)

Objective: To critically evaluate the effect of limb dominance on change of direction (COD) biomechanics associated with increased ACL injury-risk., Methods: A systematic review of the literature was conducted using Medline and Sport DISCUS databases. Studies that compared COD biomechanics (lower-limb/whole-body kinetics/kinematics) between limbs, contained an approach run, and included physically active participants were included., Results: Of the 456 articles identified, six were included. All studies investigated a cutting action, while the majority defined limb dominance as the preferred kicking limb, whereas one study defined limb dominance as preferred push-off cutting limb. Conflicting observations were found, with one study indicating the non-dominant and one study indicating the dominant limb displayed biomechanical deficits associated with increased non-contact ACL injury-risk during COD. Conversely, the remaining studies demonstrated no significant or substantial differences in COD biomechanics between limbs., Conclusions: Female soccer players, male rugby players, and female handball players exhibit subtle side-to-side differences when performing cutting manoeuvres. However, the limb displaying high-risk mechanics is inconsistent within and between studies and populations. Thus, it remains inconclusive for COD that limb dominance is an ACL injury-risk factor and whether a particular limb is of heightened injury-risk., Level of Evidence: Level 2, Systematic review., (Copyright © 2019 Elsevier Ltd. All rights reserved.)

Objective: This study compared neuromuscular control under two fatigue protocols during anticipated and unanticipated change of direction (COD) maneuvers and evaluated their effects on the risk of non-contact ACL injuries. Method: Forty-five female soccer players (mean age: 22.22 ± 2.24 years; mean height: 166.24 ± 3.33 cm; mean mass: 59.84 ± 5.03 kg) were divided into three groups: functional fatigue (Soccer specific fatigue ptotocol-SOFT90), non-functional fatigue (Bruce protocol), and control group. Before and after the implementation of neuromuscular control fatigue protocols were evaluated using the cutting motion assessment score tool (CMAS). Two-dimensional (2D) videos were recorded during anticipated and unanticipated COD trials for both dominant and non-dominant legs. Results: Significant time effects (p < 0.05) and group-time interactions (p < 0.05) were observed in both anticipated and unanticipated conditions for both dominant and non-dominant legs after the fatigue protocols. The functional fatigue group exhibited higher CMAS changes, indicating poorer movement quality following fatigue. Notably, the non-dominant leg displayed amplified deficits during unanticipated COD maneuvers following the functional fatigue protocol. Conclusions: Fatigue significantly impairs neuromuscular control, particularly in unanticipated COD situations, which increases the risk of non-contact ACL injuries. To mitigate this risk, coaches, trainers, and medical professionals should prioritize targeted training and injury prevention strategies, focusing on the non-dominant leg during unanticipated COD maneuvers. [ABSTRACT FROM AUTHOR]

Background: Change of direction (COD) movements are associated with non-contact anterior cruciate ligament (ACL) injuries in multidirectional sports. Females appear at increased risk compared to males, which could be attributable to whole body kinematic strategies and greater multiplanar knee joint loads (KJLs) during COD which can increase ACL loading. Objective: The aim of this systematic review and meta-analysis was to examine and quantitatively synthesise the evidence for differences between males and females regarding KJLs and their biomechanical determinants (whole body kinematic strategies determining KJLs) during COD tasks. Methods: Databases including SPORTDiscus, Web of Science, and PubMed were systematically searched (July 2021–June 2023) for studies that compared differences in knee joint loads and biomechanical determinants of KJLs during COD between males and females. Inclusion criteria were: (1) females and males with no prior history of ACL injury (18–40 years); (2) examined biomechanical determinants of KJLs and/ or KJLs during COD tasks > 20°; (3) compared ≥ 1 outcome measure between males and females. Studies published between 2000 and 2023 examining a cutting task > 20° with a preceding approach run that compared KJLs or the whole body multiplanar kinematics associated with them, between sexes, using three-dimensional motion analysis. Results: This meta-analysis included 17 studies with a pooled sample size of 451 participants (227 males, 224 females). Meta-analysis revealed females displayed significantly less peak knee flexion during stance (SMD: 0.374, 95% CI 0.098–0.649, p = 0.008, I2: 0%); greater knee abduction at initial contact (IC) (SMD: 0.687, 95% CI 0.299–1.076, p = 0.001, I2: 55%); less hip internal rotation (SMD: 0.437, 95% CI 0.134–0.741, p = 0.005, I2: 34%) and hip abduction at IC (SMD: −0.454, 95% CI 0.151–0.758, p = 0.003, I2: 33%). No significant differences were observed between males and females for any internal or externally applied KJLs. All retrieved studies failed to control for strength, resistance training or skill history status. Conclusion: No differences were observed in KJLs between males and females despite females displaying greater knee abduction at IC and less peak knee flexion during the stance phase of CODs, which are visual characteristics of non-contact ACL injury. Further research is required to examine if this translates to a similar injury risk, considering morphological differences in strain characteristics of the ACL between males and females. This observation may in part explain the disproportionate ACL injury incidence in female multidirectional athletes. Further higher quality controlled research is required whereby participants are matched by skill training history, resistance training history and strength status to ensure an appropriate comparison between males and females. Key Points: No differences between sexes were found for multiplanar KJLs despite previous research supporting this. Further research is required to identify if this is the case and if it affects injury risk between males and females. Females displayed greater knee abduction at initial contact, less peak knee flexion during stance, and less hip rotation and abduction at IC together with less peak hip flexion during stance during CODs. Previous research has failed to account for confounding factors such as skill training history, resistance training history and strength status together with gendered environmental factors that could contribute to the misinterpretation of COD differences between males and females. [ABSTRACT FROM AUTHOR]

Thomas, C, DosSantos, T, Comfort, P, and Jones, PA. Effect of asymmetry on biomechanical characteristics during 180° change of direction. J Strength Cond Res 34(5): 1297-1306, 2020-The aim of this study was to explore the effect of asymmetry on biomechanical characteristics during two 180° change of direction (CoD) tasks (505 and modified 505 [505mod]). Fifty-two male (n5 24; age 5 22.1 6 4.8 years; height 5 1.78 6 0.06 m; body mass 5 76.9 6 10.8 kg) and female (n 5 28; age 5 19.1 6 1.7 years; height 5 1.67 6 0.06 m; body mass 5 60.4 6 7.4 kg) team-sport players were recruited for this investigation. Three-dimensional motion data using 10 Qualisys Oqus 7 infrared cameras (240 Hz) and ground reaction force (GRF) data from 2 AMTI force platforms (1,200 Hz) were collected to analyze penultimate contacts (PEN) and final foot contacts. A series of repeated-measures analysis of variance were used to examine for differences in each dependent variable. Significant differences existed between dominant (D) and nondominant (ND) limbs for knee abduction angle (KAA) during 505mod (p 5 0.048), while significant differences existed for peak horizontal and vertical GRF (vGRF) (p , 0.001) during 505. For both tasks, the PEN involved significantly greater peak vGRF, hip flexion angles, hip extensor moments, knee flexion angles, and knee extensor moments, but lower average vGRF, horizontal GRF, and peak ankle extensor moments. For 505, the ND limb involved significantly greater peak vGRF, but the opposite was revealed for peak horizontal GRF. For 505mod, the D limb involved significantly greater KAAs. Finally, there was a significant interaction (group3 limb) for peak horizontal GRF ratio during 505. For both tasks, there was no interaction or main effects for time to completion. Therefore, it appears asymmetry influences GRFs and KAAs, but not completion time during 180° CoD in team-sport players [ABSTRACT FROM AUTHOR]

Background: Cutting actions are associated with non-contact ACL injuries in multidirectional sports due to the propensity to generate large multiplanar knee joint loads (KJLs) that have the capacity to increase ACL loading and strain. Numerous studies have investigated the biomechanical determinants of KJLs in cutting tasks. The aim of this systematic review was to comprehensively review the literature regarding biomechanical determinants of KJLs during cutting, in order to develop a cutting technical framework alongside training recommendations for practitioners regarding KJL mitigation. Methods: Databases (SPORTDiscus, Web of Science and PubMed) were systematically searched using a combination of the following terms: "Biomechanical determinants", or "Knee abduction moment", or "Technical determinants", or "Knee loading", or "Knee loads", or "Mechanical determinants", or "ACL strain", or "Knee adduction moment", or "Anterior tibial shear", or "Knee internal rotation moment", or "Knee valgus moment" AND "Change of direction", or "Cutting manoeuvre", or "Run and cut", or "Run-and-cut", or "Sidestepping", or "Side-stepping", or "Shuttle run". Inclusion criteria were as follows: studies examining a cutting task < 110° with a preceding approach run that examined biomechanical determinants of KJLs using three-dimensional motion analysis. Results: The search returned 6404 possibly eligible articles, and 6 identified through other sources. Following duplicate removal, 4421 titles and abstracts were screened, leaving 246 full texts to be screened for inclusion. Twenty-three full texts were deemed eligible for inclusion and identified numerous determinants of KJLs; 11 trunk, 11 hip, 7 knee, 3 multiplanar KJLs, 5 foot/ankle and 7 identifying ground reaction forces (GRFs) as determinants of KJLs. Conclusion: Using the framework developed from the results, cutting KJLs can be mitigated through the following: reducing lateral foot-plant distances, thus lowering hip abduction and orientating the foot closer to neutral with a mid-foot or forefoot placement strategy; minimising knee valgus and hip internal rotation angles and motion at initial contact (IC) and weight acceptance (WA); avoiding and limiting lateral trunk flexion and attempt to maintain an upright trunk position or trunk lean into the intended direction; and finally, reducing GRF magnitude during WA, potentially by attenuation through increased knee flexion and emphasising a greater proportion of braking during the penultimate foot contact (PFC). [ABSTRACT FROM AUTHOR]