Search

Your search keyword '"Antibiotics, Antitubercular"' showing total 25,109 results
Start Over Descriptor "Antibiotics, Antitubercular" Topic anti-bacterial agents
25,109 results on '"Antibiotics, Antitubercular"'

2. [The analysis of species identification and susceptibility testing of Mycobacterium abscessus].

Author

Nie W, Duan H, Huang H, Lu Y, and Chu N

Subjects
Amikacin pharmacology, Antibiotics, Antitubercular, Azithromycin pharmacology, Cefoxitin pharmacology, Clarithromycin pharmacology, Humans, Nontuberculous Mycobacteria drug effects, Nontuberculous Mycobacteria growth & development, RNA, Ribosomal, 16S, Anti-Bacterial Agents pharmacology, Nontuberculous Mycobacteria classification
Abstract

Objectives: To evaluate the method of differentiating Mycobacterium abscessus subsp. abscessus (subsp. M. abscessus) from Mycobacterium abscessus subsp. massiliense (subsp. M. massiliense), and to investigate the activity of different antibiotics in vitro., Methods: Sixty Mycobacterium abscessus (M. abscessus) isolates previously identified by using 16S rRNA sequence, were identified by comparative sequence analysis of rpoB and hsp65, and were divided into subsp. M. abscessus and subsp. M. massiliense. Two subspecies' resistant proportions were compared by chi-square test. Finally the relationship between clarithromycin resistance and erm(41) was analyzed., Results: Of all the 60 M. abscessus isolates, 65% (39/60) belonged to subsp. M. abscessus, 35% (21/60) belonged to subsp. M. massiliense. 97% (38/39) subsp. M. abscessus and 95% (20/21) subsp. M. massiliense were susceptible to amikacin. 92% (36/39) subsp. M. abscessus and 95% (20/21) subsp. M. massiliense were susceptible to azithromycin. 74% (29/39) subsp. M. abscessus and 67% (14/21) subsp. M. massiliense were susceptible to imipenem. 46% (18/39) subsp. M. abscessus and 76% (16/21) subsp. M. massiliense were moderately susceptible to cefoxitin. 82% (32/39) subsp. M. abscessus were resistant to clarithromycin, and 95% (20/21) subsp. M. massiliense were susceptible to clarithromycin. Of all the 28 subsp. M. abscessus isolates which were sequenced suscessfully, 23 isolates were resistant to clarithromycin, and 22 isolates in them had T28 in erm(41), and the rest one had C28 in erm(41). However, all the 5 subsp. M. abscessus isolates which were susceptible to clarithromycin had C28 in erm(41)., Conclusions: M. abscessus can be divided into subsp. M. abscessus and subsp. M. massiliense by using rpoB and hsp65. Amikacin, azithromycin and imipenem showed excellent inhibition activity against M. abscessus in vitro. Cefoxitin also showed a good inhibition activity. Clarithromycin had a poor inhibition activity against subsp. M. abscessus, but a good inhibition activity against subsp. M. massiliense. Erm(41) was related to clarithromycin resistance.

Published
2014

3. Importance of the thiomorpholine introduction in new pyrrole derivatives as antimycobacterial agents analogues of BM 212.

Author

Biava M, Cesare Porretta G, Deidda D, Pompei R, Tafi A, and Manetti F

Subjects
Antibiotics, Antitubercular, Antifungal Agents chemical synthesis, Antifungal Agents pharmacology, Antitubercular Agents pharmacology, Antiviral Agents chemical synthesis, Antiviral Agents pharmacology, Binding Sites, Chemical Phenomena, Chemistry, Physical, Indicators and Reagents, Isoniazid pharmacology, Microbial Sensitivity Tests, Models, Molecular, Molecular Conformation, Rifampin pharmacology, Streptomycin pharmacology, Structure-Activity Relationship, Anti-Bacterial Agents chemical synthesis, Anti-Bacterial Agents pharmacology, Morpholines chemical synthesis, Morpholines pharmacology, Mycobacterium drug effects, Piperazines chemistry, Piperazines pharmacology, Pyrroles chemical synthesis, Pyrroles chemistry, Pyrroles pharmacology
Abstract

During the course of our investigations in the field of azole antimicrobial agents, we have identified BM 212, a pyrrole derivative with good in vitro activity against mycobacteria and candidae. These findings prompted us to prepare new pyrrole derivatives 1-10 in the hope of increasing the activity. The microbiological data showed interesting in vitro activity against Mycobacterium tuberculosis and atypical mycobacteria.

Published
2003
Full Text
View/download PDF

13. The action of antibiotics on Bacterium coli infections associated with obstetrical and gynaecological conditions; terramycin and combined streptomycin and terramycin.

Author

SMITH JA and SMITH J

Subjects
Female, Humans, Anti-Bacterial Agents, Antibiotics, Antitubercular, Bacteriology, Escherichia coli, Escherichia coli Infections, Genital Diseases, Female complications, Gynecology, Obstetric Labor Complications, Oxytetracycline therapeutic use, Streptomycin therapeutic use, Urinary Tract microbiology
Published
1954
Full Text
View/download PDF

14. Tuberculosis of the larynx.

Author

SCHWARZBART AA

Subjects
Humans, Anti-Bacterial Agents therapeutic use, Antibiotics, Antitubercular, Larynx, Tuberculosis, Tuberculosis, Laryngeal therapy
Published
1953

19. [Treatment of acute pyelonephritis].

Author

FRITEL D

Subjects
Humans, Acute Disease, Anti-Bacterial Agents, Antibiotics, Antitubercular, Kidney Papillary Necrosis, Pyelonephritis
Published
1963

25. [Antibiotics in venereal diseases].

Author

QUIROGA MJ

Subjects
Anti-Bacterial Agents therapeutic use, Antibiotics, Antitubercular, Dermatologic Agents, Sexually Transmitted Diseases therapy
Published
1952

28. Antibiotics and bizarre mastoiditis.

Author

POULIN JE

Subjects
Humans, Anti-Bacterial Agents toxicity, Antibiotics, Antitubercular, Dermatologic Agents, Mastoiditis etiology, Otitis Media therapy
Published
1959

30. Experimental treatment with luteomycin.

Author

NAKASE Y and HATA T

Subjects
Anti-Bacterial Agents, Antibiotics, Antitubercular, Dermatologic Agents, Therapies, Investigational
Published
1952

32. [ON THE SUBJECT OF ENCEPHALIC VENOUS PATHOLOGY].

Author

DELLORUSSO G and DEMARIA F

Subjects
Adolescent, Humans, Anti-Bacterial Agents, Antibiotics, Antitubercular, Anticoagulants, Anticonvulsants, Cerebral Angiography, Cerebrovascular Disorders, Electroencephalography, Prednisone, Seizures, Thrombophlebitis, Vasodilator Agents
Published
1964

42. [Mycosis fungoides; curious action of mycostatin].

Author

JAUSION H, BENARD P, ROUSSEL A, and NADAL C

Subjects
Humans, Anti-Bacterial Agents therapeutic use, Antibiotics, Antitubercular, Dermatologic Agents, Exploratory Behavior, Mycosis Fungoides therapy, Nystatin
Published
1956

44. ACUTE APPENDICITIS IN THE VERY YOUNG.

Author

QUINTNER JL and WRIGHT JE

Subjects
Child, Humans, Infant, Prognosis, Acute Disease, Anti-Bacterial Agents, Antibiotics, Antitubercular, Appendectomy, Appendicitis, Diagnosis, Drug Therapy, Morbidity, Mortality, Pathology, Postoperative Complications, Surgical Wound Infection
Published
1965

47. CAUSES OF UNSUCESSFUL ANTIMICROBIAL THERAPY.

Author

FLIPPIN HF

Subjects
Anti-Bacterial Agents, Anti-Infective Agents, Antibiotics, Antitubercular, Bacteriological Techniques, Drug Hypersensitivity, Drug Resistance, Microbial, Toxicology
Published
1964

Catalog

Books, media, physical & digital resources
See catalog results