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Your search keyword '"Maiti, Samarendra N."' showing total 2 results
Start Over Author "Maiti, Samarendra N." Topic anti-bacterial agents
2 results on '"Maiti, Samarendra N."'

1. Synthesis and SAR of novel conformationally-restricted oxazolidinones possessing gram-positive and fastidious gram-negative antibacterial activity. Part 1: Substituted pyrazoles.

Author

Boyer FE, Vara Prasad JV, Choy AL, Chupak L, Dermyer MR, Ding Q, Huband MD, Jiao W, Kaneko T, Khlebnikov V, Kim JY, Lall MS, Maiti SN, Romero K, and Wu X

Subjects
Molecular Structure, Pyrazoles chemistry, Structure-Activity Relationship, Anti-Bacterial Agents chemistry, Anti-Bacterial Agents pharmacology, Gram-Negative Bacteria drug effects, Gram-Positive Bacteria drug effects, Oxazolidinones chemistry, Oxazolidinones pharmacology, Pyrazoles pharmacology
Abstract

A novel series of conformationally-restricted oxazolidinones was synthesized which possess a fused pyrazole ring substituted with various alkyl, aryl and heteroaryl substituents. A number of analogs exhibited potent activity against both gram-positive and fastidious gram-negative organisms.

Published
2007
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2. Synthesis and structure-activity studies of novel benzocycloheptanone oxazolidinone antibacterial agents.

Author

Vara Prasad JV, Boyer FE, Chupak L, Dermyer M, Ding Q, Gavardinas K, Hagen SE, Huband MD, Jiao W, Kaneko T, Maiti SN, Melnick M, Romero K, Patterson M, and Wu X

Subjects
Anti-Bacterial Agents chemistry, Benzocycloheptenes chemistry, Gram-Negative Bacteria drug effects, Gram-Positive Bacteria drug effects, Microbial Sensitivity Tests, Molecular Structure, Oxazolidinones chemistry, Structure-Activity Relationship, Anti-Bacterial Agents chemical synthesis, Anti-Bacterial Agents pharmacology, Benzocycloheptenes chemical synthesis, Benzocycloheptenes pharmacology, Oxazolidinones chemical synthesis, Oxazolidinones pharmacology
Abstract

We describe a novel class of benzocycloheptanone derived oxazolidinone antibacterial agents. The synthesis and antibacterial activities with structure variation is discussed.

Published
2006
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