1. Isolation of guaianoid pigments from the gorgonian Calicogorgia granulosa.
- Author
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Seo Y, Rho JR, Geum N, Yoon JB, and Shin J
- Subjects
- Animals, Anti-Bacterial Agents, Anti-Infective Agents pharmacology, Antifungal Agents isolation & purification, Antifungal Agents pharmacology, Azulenes, Bacillus subtilis drug effects, Candida albicans drug effects, Escherichia coli drug effects, Microbial Sensitivity Tests, Sesquiterpenes pharmacology, Sesquiterpenes, Guaiane, Anti-Infective Agents isolation & purification, Cnidaria chemistry, Sesquiterpenes isolation & purification
- Abstract
Three pigments of the guaiazulene class have been isolated from the gorgonian Calicogorgia granulosa. Structures of these compounds have been determined as guaiazulene, 2,2'- diguaiazulenylmethane, and a new compound, 2,2'-biguaiazulenyl, by combined chemical and spectroscopic methods. 2,2'-Biguaiazulenyl exhibited moderate antimicrobial activity.
- Published
- 1996
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