1. Scleritis complicating zoledronic acid infusion.
- Author
-
Benderson D, Karakunnel J, Kathuria S, and Badros A
- Subjects
- Aged, Bone Density Conservation Agents administration & dosage, Humans, Imidazoles administration & dosage, Male, Multiple Myeloma complications, Multiple Myeloma diagnostic imaging, Multiple Myeloma drug therapy, Pamidronate, Radiography, Scleritis chemically induced, Scleritis diagnostic imaging, Zoledronic Acid, Anti-Inflammatory Agents administration & dosage, Bone Density Conservation Agents adverse effects, Diphosphonates administration & dosage, Diphosphonates adverse effects, Imidazoles adverse effects, Scleritis drug therapy
- Abstract
We present a case of severe unilateral posterior scleritis associated with zoledronic acid administration that was recognized and treated in a timely manner. Subsequent use of pamidronate was associated with milder inflammation in the same eye that eventually resolved with continued monthly infusions, indicating the possibility of immunologic tolerance. Physicians prescribing these drugs should be aware of this side effect, which, if not recognized and treated appropriately, is potentially devastating. We review the published data as well as the current treatment recommendations.
- Published
- 2006
- Full Text
- View/download PDF