Search

Your search keyword '"Liu, Bao-Hui"' showing total 1 results
Start Over Author "Liu, Bao-Hui" Topic antibacterial agents
1 results on '"Liu, Bao-Hui"'

1. Synthesis, crystal structures, and anti-drug-resistant Staphylococcus aureus activities of novel 4-hydroxycoumarin derivatives.

Author

Li, Ming-kai, Li, Jing, Liu, Bao-hui, Zhou, Ying, Li, Xia, Xue, Xiao-yan, Hou, Zheng, and Luo, Xiao-xing

Subjects
*DRUG synthesis, *CRYSTAL structure, *STAPHYLOCOCCUS aureus, *COUMARIN derivatives, *X-ray crystallography, *ANTIBACTERIAL agents
Abstract

Abstract: Four novel 4-hydroxycoumarin derivatives (4-MBH, 3-MBH, 4-MDT and 3-MDT) were successfully synthesized and their structures were verified by single-crystal X-ray crystallography. All target compounds were evaluated for their in vitro antibacterial activity against Staphylococcus aureus (S. aureus ATCC 29213), methicillin-resistant S. aureus (MRSA XJ 75302), vancomycin-intermediate S. aureus (Mu50 ATCC 700699), and USA 300 (Los Angeles County clone, LAC). The minimum inhibitory concentration and time–kill curves were obtained for the test compounds and antibiotics. Among the tested compounds, 3-MBH showed the most potent antibacterial activities. [Copyright &y& Elsevier]

Published
2013
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results