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1. Characterization of monoclonal antibodies to bovine viral diarrhoea virus: evidence of a neutralizing activity against gp48 in the presence of goat anti-mouse immunoglobulin serum.

Author

Boulanger D, Waxweiler S, Karelle L, Loncar M, Mignon B, Dubuisson J, Thiry E, and Pastoret PP

Subjects
Animals, Antibodies, Anti-Idiotypic, Cattle, Cross Reactions, Enzyme-Linked Immunosorbent Assay, Fluorescent Antibody Technique, Goats, Mice, Neutralization Tests, Radioimmunoprecipitation Assay, Antibodies, Monoclonal immunology, Diarrhea Viruses, Bovine Viral immunology, Immunoglobulins immunology, Viral Envelope Proteins immunology
Abstract

Twenty-one monoclonal antibodies (MAbs) directed against the NY-1 and the Osloss-c strains of bovine viral diarrhoea virus were produced and characterized by indirect immunofluorescence assay, radioimmunoprecipitation and neutralization tests. Fourteen MAbs directed against the NY-1 strain recognized the gp48 and showed a weak neutralizing activity in the presence of goat anti-mouse immunoglobulin serum.

Published
1991
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