1. Chinese Hamster Ovary Cells: Explore the techniques and considerations Involved in Harnessing their Potential for Monoclonal Antibodies Production.
- Author
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Rajaganapathy, K., Balaji, P., Dhanapal, Shyam Sundar, Saravanan, G., Monisha, J., Shanmugasundaram, P., and Srinivasan, R.
- Subjects
CHO cell ,MONOCLONAL antibodies ,ANTIBODY formation ,POST-translational modification - Abstract
Chinese Hamster Ovary (CHO) cells have proven to be a remarkable tool in the production of monoclonal antibodies, offering numerous advantages such as high expression levels and post-translational modifications. Through the utilization of advanced techniques, researchers have been able to optimize CHO cell cultures for enhanced antibody production. However, it is crucial to consider various factors such as media composition, cell line engineering, and bioprocess optimization to achieve optimal results. By carefully addressing these considerations, researchers can harness the full potential of CHO cells for the production of high-quality monoclonal antibodies. Thus, the field of biotechnology continues to advance at an astonishing pace, the production of monoclonal antibodies holds immense promise for revolutionizing medicine. These highly specific molecules have become indispensable tools in diagnostics, therapeutics, and research. However, their production requires careful consideration of various factors to ensure optimal yield and quality. In this article, we delve into the world of Chinese Hamster Ovary (CHO) cells and explore the techniques and considerations involved in harnessing their potential for monoclonal antibody production. [ABSTRACT FROM AUTHOR]
- Published
- 2023