Search

Selenium is a trace and necessary micronutrient for human, animal, and microbial health. Many researchers have recently been interested in selenium nanoparticles (SeNPs) due to their biocompatibility, bioavailability, and low toxicity. As a result of their greater bioactivity, selenium nanoparticles are widely employed in a variety of biological applications. Physical, chemical, and biological approaches can all be used to synthesize selenium nanoparticles. Since it uses non-toxic solvents and operates at a suitable temperature, the biological technique is a preferable option. This review article addresses the processes implemented in the synthesis of SeNPs and highlights their medicinal uses, such as the treatment of fungi, bacteria, cancer, and wounds. Furthermore, we discuss the most recent findings on the potential of several biological materials for selenium nanoparticle production. The precursor, extract, process, time, temperature, and other synthesis criteria will be elaborated in conjunction with the product's physical properties (size, shape, and stability). The synergies of SeNP synthesis via various methods aid future researchers in precisely synthesizing SeNPs and using them in desired applications. [ABSTRACT FROM AUTHOR]

Zingiberaceae species are widely in traditional medicine throughout the world. This study evaluates the potential biological applications of phyto-functionalised silver nanoparticles (AgNPs) synthesised using sprouted Zingiberaceae species. The AgNPs were characterised and found to be spherical in the size of 25 nm-30 nm. The experimental results indicated that AgNPs have notable bactericidal activity against gram-positive and gram-negative bacteria. Human colon cancer cells (HCT15) were used to perform the anticancer assay and cell viability at a concentration of 500 µg/mL ranged from 43.71% to 49.49%. Also sprouted C. amada AgNPs at a concentration of 200 μg/mL provided maximum inhibition of 65.40% and 68.78% for α-amylase and α-glucosidase activity respectively. Furthermore, the sprouted Z. officinale AgNPs at a concentration of 500 µg/mL displayed significant glucose uptake percentage (99.56%) under in vitro conditions. The results indicated that phyto-functionalised AgNPs from sprouted Z. officinale and C. amada possess antibacterial, anticancer and antidiabetic activity. [ABSTRACT FROM AUTHOR]