1. Acremonium sclerotigenum-Acremonium egyptiacum: a multi-resistant fungal pathogen complicating the course of aplastic anaemia.
- Author
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Guitard J, Degulys A, Buot G, Aline-Fardin A, Dannaoui E, Rio B, Marie JP, Lapusan S, and Hennequin C
- Subjects
- Acremonium classification, Adult, Anemia, Aplastic microbiology, Caspofungin, Drug Resistance, Fungal drug effects, Humans, Lipopeptides, Male, Mycoses drug therapy, Opportunistic Infections drug therapy, Pyrimidines therapeutic use, Triazoles therapeutic use, Voriconazole, Acremonium isolation & purification, Amphotericin B therapeutic use, Anemia, Aplastic complications, Antifungal Agents therapeutic use, Echinocandins therapeutic use, Mycoses microbiology, Opportunistic Infections microbiology, Pyrimidines pharmacology, Triazoles pharmacology
- Abstract
A patient with aplastic anaemia, successively treated with caspofungin then liposomal amphotericin, developed a disseminated infection due to Acremonium, further confirmed as resistant in vitro to these drugs. Successful treatment was achieved with voriconazole. Multiple antifungal treatments may expose to the risk of breakthrough of multi-resistant pathogens in haematology patients., (© 2013 The Authors Clinical Microbiology and Infection © 2013 European Society of Clinical Microbiology and Infectious Diseases.)
- Published
- 2014
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