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2 results on '"Zarrella I"'

1. Bactericidal and Fungicidal Activity in the Gas Phase of Sodium Dichloroisocyanurate (NaDCC).

Author

Proto A, Zarrella I, Cucciniello R, Pironti C, De Caro F, and Motta O

Subjects
Disinfectants chemistry, Disinfectants pharmacology, Escherichia coli drug effects, Fungi drug effects, Gases chemistry, Gases pharmacology, Microbial Sensitivity Tests, Staphylococcus aureus drug effects, Triazines chemistry, Anti-Bacterial Agents chemistry, Anti-Bacterial Agents pharmacology, Antifungal Agents chemistry, Antifungal Agents pharmacology, Triazines pharmacology
Abstract

Sodium dichloroisocyanurate (NaDCC) is usually employed as a disinfectant for the treatment of water, environmental surfaces and medical equipment principally for its effectiveness as a microbicide agent. In this study, we explore the possibility of a new use for NaDCC by investigating the microbicidal activity of chlorine, which derives from the hydrolysis of NaDCC mediated by air humidity, and by testing its effect on the neutralization of microbes present in domestic waste. NaDCC was inserted in a plastic garbage can where LB agar plates, with different dilutions of a known title of four different microorganisms (Escherichia coli, Staphylococcus aureus, Debaryomyces hansenii and Aspergillus brasiliensis), were weakly inserted. The molecular chlorine (Cl2) levels present in the garbage can were quantified using an iodometric titration. The gas emitted in the garbage can presented a strong microbicide effect, inhibiting the proliferation of all four microorganisms and for four consecutive weeks, thus showing that NaDCC hydrolysis, mediated by air humidity, is able to ensure the decontamination of restricted environments, avoiding the proliferation of both Gram-positive and Gram-negative bacteria as well as fungi.

Published
2016
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2. Study of the antibacterial activity in the gas phase of a chemical formulation for household waste management.

Author

Motta O, Zarrella I, Cucciniello R, Vigliotta G, and Proto A

Subjects
2-Propanol pharmacology, Acrolein analogs & derivatives, Acrolein pharmacology, Cyclohexenes pharmacology, Limonene, Microbial Sensitivity Tests, Terpenes pharmacology, Anti-Bacterial Agents pharmacology, Antifungal Agents pharmacology, Debaryomyces drug effects, Escherichia coli drug effects, Penicillium drug effects, Staphylococcus aureus drug effects, Waste Management methods
Abstract

Unlabelled: The aim of this study was to formulate a product (microbicide mixture) that could slow down the bacterial proliferation during the storage of household waste. We used harmless and natural components, known for their antimicrobial properties, in the liquid phase at direct contact with the microbes. The antimicrobial activity of the microbicide mixture formulated was evaluated over a range of concentration in two types of tests, in the liquid and in the gas phase. Once the efficacy of antimicrobial agent in the liquid phase in direct contact with the microbe (Escherichia coli) was confirmed, we adopted a new approach to evaluate the effect of the vapour phase both on the microbes' growth and on its duration. Here, we show that the perfect combination that gives rise to an antimicrobial mixture useful to control microbial growth (Staphylococcus aureus, Escherichia coli, Debaryomyces hansenii or Penicillium citrinum) up to 4 weeks is the one between more volatile agents (2-propanol and limonene) and a less volatile agent (cinnamaldehyde). The pleasant smell as well as the synergic antibacterial and antifungal function of the natural components of this mixture makes it attractive in domestic waste management., Significance and Impact of the Study: The novelty of this work is two-fold: on the one hand, to test various antimicrobial components of different volatility in a single microbicide mixture, and on the other, to study antimicrobial activity in the gas phase, other than the liquid phase. While previous authors tested the components individually as antimicrobial agents in the liquid phase at direct contact with the microbes, we tested them altogether as a mixture both in the liquid and in gas phase. The aim of this study was to disinfect small environments, such as garbage containers, by favouring the diffusion of the vapour phase to avoid the growth of microbes. This study proposes a new approach in the management and storage of household waste by inhibiting bacterial proliferation in the garbage can., (© 2014 The Society for Applied Microbiology.)

Published
2015
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