Search

A recent study conducted by researchers at Okayama University in Japan has found that short-chain fatty acids (SCFAs) produced by intestinal bacteria are responsible for the extension of dendrites by dendritic cells in the intestine. SCFAs such as acetic, propionic, butyric, and valeric acids induce dendrite elongation by inhibiting an enzyme called histone deacetylase. This discovery may have implications for identifying beneficial intestinal bacteria and developing drugs to regulate immune responses. The findings of this study could pave the way for new treatments that directly target dendritic cells. [Extracted from the article]