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Start Over Author "Reshilov LN" Topic antigens, bacterial
2 results on '"Reshilov LN"'

1. [The immunobiological properties of the antigenic preparations obtained from a vaccinal strain of Klebsiella pneumoniae 204 grown in media of differing compositions].

Author

Miriasova LV, Basnak'ian IA, Egorova NB, Kurbatova EA, Reshilov LN, Krylova AIu, Efimtseva OV, Shagam NL, and Salov VF

Subjects
Animals, Antigens, Bacterial isolation & purification, Antigens, Bacterial toxicity, Bacterial Vaccines isolation & purification, Bacterial Vaccines toxicity, Culture Media, Immunization, Klebsiella pneumoniae growth & development, Klebsiella pneumoniae ultrastructure, Lethal Dose 50, Mice, Microscopy, Electron, Antigens, Bacterial immunology, Bacterial Vaccines immunology, Klebsiella pneumoniae immunology
Abstract

In the technology of the cultivation of K. pneumoniae vaccine strain 204 with a view to obtaining biomass for the production of antigenic preparations the traditionally used culture medium with full nutritional value has been replaced by the alternative variant of synthetic medium. The specific physiological and morphological features of this strain grown in synthetic culture medium have been studied and described. Irrespective of the composition of the culture media used for cultivation, the antigenic preparations have been shown to have no difference in their chemical composition, immunogenic and toxic properties.

Published
1990

2. [Comparative analysis of antigenic preparations made from noncapsular strains of Pneumococcus].

Author

Nisilevich VF, Pugacheva NL, Padiukov LN, Gruber IM, and Reshilov LN

Subjects
Animals, Antibodies, Bacterial analysis, Antigens, Bacterial isolation & purification, Bronchitis diagnosis, Cross Reactions, Epitopes analysis, Humans, Immunization, Mice, Microscopy, Electron, Pneumococcal Infections diagnosis, Rabbits, Rheumatic Diseases diagnosis, Serotyping, Streptococcus pneumoniae classification, Streptococcus pneumoniae ultrastructure, Antigens, Bacterial analysis, Streptococcus pneumoniae immunology
Abstract

Nonencapsulated strains obtained by subculturing Streptococcus pneumoniae in a medium containing 0.5% of bile have been shown to possess a number of morphological and cultural features. The preparations obtained from the biomass of these strains by sonication have been found to possess antigenic, immunogenic and protective properties and to be specific to S. pneumoniae. The data obtained in this investigation may be considered indicative of the necessity for further study of these preparations with a view to their use for the analysis of serum samples taken from patients with bronchopulmonary diseases by means of enzyme immunoassay.

Published
1987

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