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Your search keyword '"Mastropietro TF"' showing total 2 results
Start Over Author "Mastropietro TF" Topic antineoplastic agents
2 results on '"Mastropietro TF"'

1. Non-classical anticancer agents: on the way to water soluble zinc(II) heteroleptic complexes.

Author

Sanz Mendiguchia B, Pucci D, Mastropietro TF, Ghedini M, and Crispini A

Subjects
2,2'-Dipyridyl chemistry, Antineoplastic Agents chemical synthesis, Coordination Complexes chemical synthesis, Crystallography, X-Ray, Molecular Conformation, Saccharin chemistry, Water chemistry, Antineoplastic Agents chemistry, Coordination Complexes chemistry, Zinc chemistry
Abstract

Two new heteroleptic Zn(II) complexes of the 4,4'-bis(hydroxymethyl)-2,2'-bipyridine have been synthesized by using different stoichiometric ratios of tropolone. In an attempt to induce the formation of metal complex co-crystals, liquid assisted solid state reaction followed by solvent crystallization has been conducted by using the new Zn(II) tropolonate derivatives 1 and 2 with saccharin. The novel Zn(II) species obtained exhibits different structures and properties with respect to their precursors, due to a hydrogen exchange between saccharin and the tropolonate coordinated ligand.

Published
2013
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2. Rhenium(IV) compounds inducing apoptosis in cancer cells.

Author

Martínez-Lillo J, Mastropietro TF, Lappano R, Madeo A, Alberto ME, Russo N, Maggiolini M, and De Munno G

Subjects
Humans, Ligands, Molecular Structure, 2,2'-Dipyridyl chemistry, 2,2'-Dipyridyl pharmacology, Antineoplastic Agents chemistry, Antineoplastic Agents pharmacology, Apoptosis drug effects, Cell Line, Tumor drug effects, Organometallic Compounds chemistry, Organometallic Compounds pharmacology, Phenanthrolines chemistry, Phenanthrolines pharmacology, Pyridines chemistry, Pyridines pharmacology, Rhenium chemistry
Abstract

The anticancer properties of a series of mononuclear Re(IV) compounds of formula ReCl(4)L (where L is bpy = 2,2'-bipyridine; bpym = 2,2'-bipyrimidine; dmbpy = 4,4'-dimethyl-2,2'-bipyridine; phen = 1,10-phenanthroline) were investigated for the first time. All compounds displayed potent in vitro antiproliferative activity against selected cancer cells., (© The Royal Society of Chemistry 2011)

Published
2011
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