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Your search keyword '"Ubiquitins antagonists & inhibitors"' showing total 13 results

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13 results on '"Ubiquitins antagonists & inhibitors"'

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1. Realgar transforming solution-induced differentiation of NB4 cell by the degradation of PML/RARα partially through the ubiquitin-proteasome pathway.

2. Evidence for the ISG15-Specific Deubiquitinase USP18 as an Antineoplastic Target.

3. Efficacy of NEDD8 Pathway Inhibition in Preclinical Models of Poorly Differentiated, Clinically Aggressive Colorectal Cancer.

4. Small molecule therapeutics targeting F-box proteins in cancer.

5. Phase I Study of the Novel Investigational NEDD8-Activating Enzyme Inhibitor Pevonedistat (MLN4924) in Patients with Relapsed/Refractory Multiple Myeloma or Lymphoma.

6. Neddylation Pathway as a Novel Anti-cancer Target: Mechanistic Investigation and Therapeutic Implication.

7. Overactivated neddylation pathway as a therapeutic target in lung cancer.

8. Negative regulation of NEDD8 conjugation pathway by novel molecules and agents for anticancer therapy.

9. Bortezomib reduces the tumorigenicity of multiple myeloma via downregulation of upregulated targets in clonogenic side population cells.

10. MLN4924: a novel first-in-class inhibitor of NEDD8-activating enzyme for cancer therapy.

11. Macroautophagy modulates cellular response to proteasome inhibitors in cancer therapy.

12. Nitric oxide regulates cell sensitivity to cisplatin-induced apoptosis through S-nitrosylation and inhibition of Bcl-2 ubiquitination.

13. Human THP-1 monocytic leukemic cells induced to undergo monocytic differentiation by bryostatin 1 are refractory to proteasome inhibitor-induced apoptosis.

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