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1. De-Differentiation Confers Multidrug Resistance Via Noncanonical PERK-Nrf2 Signaling.

Author

Del Vecchio, Catherine A., Feng, Yuxiong, Sokol, Ethan S., Tillman, Erik J., Sanduja, Sandhya, Reinhardt, Ferenc, and Gupta, Piyush B.

Subjects
*MULTIDRUG resistance, *CELL differentiation, *CANCER cells, *ANTIOXIDANTS, *REACTIVE oxygen species
Abstract

: Upregulation of PERK-Nrf2 signaling is a key mechanism by which de-differentiated cancer cells gain multi-drug resistance. [ABSTRACT FROM AUTHOR]

Published
2014
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