1. Antioxidant potentiality of three herbal teas consumed in Bandundu rural areas of Congo.
- Author
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Kapepula PM, Mbombo Mungitshi P, Franck T, Mouithys-Mickalad A, Mumba Ngoyi D, Kalenda PDT, Kabamba Ngombe N, Serteyn D, Tits M, Frédérich M, and Tamfum Muyembe JJ
- Subjects
- Chromatography, High Pressure Liquid, Chromatography, Thin Layer, Congo, Fluoresceins analysis, Free Radical Scavengers pharmacology, Glucosides analysis, HL-60 Cells, Humans, Inhibitory Concentration 50, Lantana chemistry, Lippia chemistry, Ocimum chemistry, Phenols analysis, Plant Extracts analysis, Plant Extracts chemistry, Plant Extracts pharmacology, Plant Leaves chemistry, Rural Population, Antioxidants analysis, Antioxidants pharmacology, Teas, Herbal analysis
- Abstract
The aim of this study was to evaluate and compare the cellular antioxidant activities of Lantana montevidensis, Lippia multiflora, and Ocimum gratissimum leaves often consumed as herbal teas in a rural area of Bandundu severely affected by konzo, which is related to oxidative damage. Consequently, dietary supplements with proven antioxidant potentialities could be of real interest to promote in this area. Phytochemical screening by TLC and HPLC-DAD of extracts revealed the presence of verbascoside as a major phenolic compound. Verbascoside in L. montevidensis and O. gratissimum is reported here for the first time. All extracts displayed high ABTS and DPPH radical-scavenging activities at the concentration range of 1-40 μg mL
-1 according to order: L. multiflora > O. gratissimum > L. montevidensis. L. multiflora showed the best cellular antioxidant activity using DCFH-DA on HL-60 monocytes assay at 1-20 μg mL-1 . These herbal teas may be used as nutraceuticals for their potent antioxidant activity.- Published
- 2017
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