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1. [Persistent neurological syndrome after treatment with lithium salts. Toxicity of the lithium-neuroleptic combination?].

Author

Habib M, Khalil R, le Pensec-Bertrand D, Ali-Cherif A, Bongrand MC, and Crevat A

Subjects
Adult, Bipolar Disorder drug therapy, Drug Interactions, Drug Therapy, Combination, Female, Fever complications, Humans, Male, Middle Aged, Nervous System Diseases diagnosis, Antipsychotic Agents adverse effects, Lithium adverse effects, Nervous System Diseases chemically induced
Abstract

In 2 patients receiving a long-term lithium carbonate therapy, persistent cerebellar, pyramidal, and extrapyramidal signs were observed, following a febrile pulmonary event. The mechanism of these disturbances is discussed, emphasizing the lithium-neuroleptics interaction as well as the possible role of hyperthermia.

Published
1986

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