1. Smoking, smoking cessation and aortic arch calcification in older Chinese: The Guangzhou Biobank Cohort Study
- Author
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Jiang, Chao Qiang, Lao, Xiang Qian, Yin, Peng, Thomas, G. Neil, Zhang, Wei Sen, Liu, Bin, Adab, Peymane, Lam, Tai Hing, and Cheng, Kar Keung
- Subjects
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SMOKING , *SMOKING cessation , *CALCIFICATION , *AORTIC valve , *CHEST X rays , *OLDER people - Abstract
Abstract: Objective: To study the association between smoking, smoking cessation and aortic arc calcification (AAC) in an older Chinese population. Methods: A total of 3022 men and 7279 women aged 50–85 years were recruited and received a medical check-up including measurement of fasting plasma vascular risk factors. Two radiologists reviewed the posterior–anterior plain chest X-ray radiographs and assessed AAC together. Information on smoking status, socioeconomic and lifestyle factors was collected. Results: The crude prevalence of AAC in men (38.58%) was lower than that in women (41.37%). The adjusted odds ratios of AAC increased significantly across never, ex- and current smokers in both genders. Dose–response relationships were observed among current smokers for smoking amount (cigarettes/day), smoking duration (years) and cigarette pack-years in both genders (all p <0.01). The odds ratios decreased significantly (p =0.018) with longer duration of quitting in light ex-smoking men (<23.5 pack-years) but showed no beneficial effect (p =0.72) for heavy ex-smokers (≥23.5 pack-years). Conclusion: Smoking increased the risk of AAC in Chinese, while smoking cessation decreased the risk only in male light ex-smokers. Chest X-ray is a cheap and simple method to detect AAC, which should be an important warning signal for immediate smoking cessation. [Copyright &y& Elsevier]
- Published
- 2009
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