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Your search keyword '"Muretti, Mirko"' showing total 3 results
Start Over Author "Muretti, Mirko" Topic aortic valve
3 results on '"Muretti, Mirko"'

1. Tropheryma whipplei endocarditis: An uncommon infection with potentially fatal consequences.

Author

Muretti M, Keiralla A, Jeffery K, and Krasopoulos G

Subjects
Anti-Bacterial Agents administration & dosage, Endocarditis, Bacterial complications, Endocarditis, Bacterial drug therapy, Fatal Outcome, Heart Valve Prosthesis Implantation, Humans, Male, Middle Aged, Multiple Organ Failure etiology, Rare Diseases, Aortic Valve surgery, Endocarditis, Bacterial microbiology, Endocarditis, Bacterial surgery, Tropheryma, Whipple Disease
Abstract

We report a case of culture-negative aortic valve endocarditis secondary to Tropheryma whipplei infection. Our patient underwent aortic valve replacement after 4 weeks of antibiotic therapy with persistently negative blood culture results. Despite a technically uneventful operation, the patient showed continued sepsis and was unresponsive to a broad-spectrum of antibiotic therapy with subsequent multiorgan failure. He died on the 5th postoperative day, and diagnosis was established at postmortem examination. In this case report, we discuss the diagnosis and treatment of a rare type of endocarditis caused by T. whipplei., (© 2020 Wiley Periodicals, Inc.)

Published
2020
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2. Surgical Complexity and Outcome of Patients Undergoing Re-do Aortic Valve Surgery.

Author

Greco R, Muretti M, Djordjevic J, Jin XY, Hill E, Renna M, and Petrou M

Subjects
Adult, Aged, Aged, 80 and over, Aortic Valve diagnostic imaging, Aortic Valve physiopathology, Aortic Valve Insufficiency diagnostic imaging, Aortic Valve Insufficiency mortality, Aortic Valve Insufficiency physiopathology, Aortic Valve Stenosis diagnostic imaging, Aortic Valve Stenosis mortality, Aortic Valve Stenosis physiopathology, Bioprosthesis, Female, Heart Valve Prosthesis, Hemodynamics, Hospital Mortality, Humans, Male, Middle Aged, Postoperative Complications diagnostic imaging, Postoperative Complications mortality, Postoperative Complications physiopathology, Reoperation, Retrospective Studies, Risk Factors, Time Factors, Treatment Outcome, Aortic Valve surgery, Aortic Valve Insufficiency surgery, Aortic Valve Stenosis surgery, Heart Valve Prosthesis Implantation adverse effects, Heart Valve Prosthesis Implantation instrumentation, Heart Valve Prosthesis Implantation mortality, Postoperative Complications surgery, Transcatheter Aortic Valve Replacement adverse effects, Transcatheter Aortic Valve Replacement instrumentation, Transcatheter Aortic Valve Replacement mortality
Abstract

Objectives: Re-do aortic valve surgery carries a higher mortality and morbidity compared with first time aortic valve replacement (AVR) and often requires concomitant complex procedures. Transcatheter aortic valve replacement (TAVR) is an option for selective patients. The aim of this study is to present our experience with re-do aortic valve procedures and give an insight into the characteristics of these patients and their outcomes., Methods: Retrospective review of 80 consecutive re-do aortic valve procedures., Results: Mean patients' age was 51.80±18.73 years. Aortic regurgitation (AR) was present in 51 (65.4%) patients and aortic stenosis (AS) in 38 (48.7%). Indications for reoperation were: infective endocarditis (IE) (23.8%), bioprosthetic degeneration (12.5%), mechanical valve dysfunction (5%), paravalvular leak (6.2%), patient-prosthesis mismatch (3.8%), native valve disease (25%), aortic aneurysm, pseudoaneurysm and dissection (35%), aortic root/homograft degeneration (27.5%). Forty-one (51.2%) patients underwent re-do AVR, 39 (48.8%) re-do complex aortic valve surgery (28 root, 23 ascending aorta and 6 hemiarch procedures) and 37.5% concomitant procedures. A bioprosthesis was implanted in 43.8%, a mechanical valve in 37.5%, a composite graft in 2.5%, a Biovalsalva graft in 6.2% and a homograft in 10% of patients. In-hospital mortality was 3.8% and incidence of major complications was low., Conclusions: A significant proportion of patients were young (61%<60 y), required complex aortic procedures (49%) or presented with contraindications for TAVR (mechanical valve, AR, IE, proximal aortic disease, need for concomitant surgery). Re-do aortic surgery remains the only treatment for such challenging cases and can be performed with acceptable mortality and morbidity in a specialised aortic centre., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)

Published
2020
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3. Surgical Repair of Mitral-Aortic Intervalvular Fibrosa Pseudoaneurysm in a High-Risk Patient 13 Years after Aortic Root Replacement.

Author

Muretti M, Elmahdy W, Ttofi I, Mozalbat D, Murphy M, Asimakopoulos G, and Rosendahl U

Subjects
Aneurysm, False diagnosis, Aneurysm, False etiology, Aorta, Thoracic diagnostic imaging, Aortic Valve Insufficiency surgery, Heart Aneurysm diagnosis, Heart Aneurysm etiology, Heart Valve Prosthesis Implantation adverse effects, Humans, Imaging, Three-Dimensional, Magnetic Resonance Imaging, Cine, Male, Middle Aged, Postoperative Complications, Reoperation, Tomography, X-Ray Computed, Aneurysm, False surgery, Aorta, Thoracic surgery, Aortic Valve surgery, Cardiac Surgical Procedures methods, Heart Aneurysm surgery, Mitral Valve surgery
Abstract

Pseudoaneurysms of the mitral-aortic intervalvular fibrosa are rare complications that can develop after mitral or aortic valve surgery, endocarditis, or Takayasu arteritis. The optimal timing of surgery to avoid potentially life-threatening complications of pseudoaneurysms has not been established, and watchful waiting has been adopted in specific situations. We describe the case of a 50-year-old man in whom a pseudoaneurysm of the mitral-aortic intervalvular fibrosa developed after aortic root replacement with a homograft. After 13 years of watchful waiting, reoperation was deemed necessary because the pseudoaneurysm had grown to 48 mm and the aortic regurgitation caused by the degenerated homograft had become severe. This case highlights the need for increased awareness of mitral-aortic intervalvular fibrosa pseudoaneurysms and their management.

Published
2019
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