1. Identification of apolipoprotein A-I as a target of platelet tyrosine kinases.
- Author
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Föhrkolb, Christine, Vogel, Katrin, Lochnit, Günter, and Presek, Peter
- Subjects
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PROTEIN kinase B , *PEPTIDE mass fingerprinting , *THROMBIN receptors , *HIGH density lipoproteins , *APOLIPOPROTEIN A , *LIPID rafts , *KINASES - Abstract
This document explores the phosphorylation of apolipoprotein A-I (apoA-I) by platelet tyrosine kinases. The study identifies several Src family kinases (SFKs) involved in the tyrosine phosphorylation of apoA-I in platelets, specifically at Tyr42. The authors suggest that this phosphorylation may impact apoA-I's role in platelet signaling and lipid binding, but further research is needed to determine the specific kinase responsible and understand the functional implications. The study was conducted ethically and received support from the Open Access Publication Fund of Martin-Luther-University Halle-Wittenberg. [Extracted from the article]
- Published
- 2024
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