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Your search keyword '"Tang, Yanlin"' showing total 2 results
Start Over Author "Tang, Yanlin" Topic apoptosis Topic renal cell carcinoma

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2 results on '"Tang, Yanlin"'

1. Identification of pyroptosis-related subtypes and comprehensive analysis of characteristics of the tumor microenvironment infiltration in clear cell renal cell carcinoma.

Author

Zeng, Jiayi, Zhu, Ping, Tang, Yanlin, Zhang, Changzheng, Ye, Chujin, Cheng, Shouyu, Tian, Kaiwen, Yang, Bowen, Zeng, Weinan, Liu, Yanjun, Xian, Zhiyong, and Yu, Yuming

Subjects
*RENAL cell carcinoma, *APOPTOSIS, *TUMOR microenvironment, *PROGRAMMED cell death 1 receptors, *PYROPTOSIS, *PROGNOSTIC models
Abstract

Pyroptosis is a kind of programmed cell death triggered by the inflammasome. Growing evidence has revealed the crucial utility of pyroptosis in tumors. However, the potential mechanism of pyroptosis in clear cell renal cell carcinoma (ccRCC) is still unclear. In this research, we systematically analyze the genetic and transcriptional alterations of pyroptosis-related genes (PRGs) in ccRCC, identify pyroptosis-related subtypes, analyze the clinical and microenvironmental differences among different subtypes, develop a corresponding prognostic model to predict the prognosis of patients, and interpret the effect of pyroptosis on ccRCC microenvironment. This study provides a new perspective for a comprehensive understanding of the role of pyroptosis in ccRCC and its impact on the immune microenvironment, and a reliable scoring system was established to predict patients' prognosis. [ABSTRACT FROM AUTHOR]

Published
2023
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2. Identification of pyroptosis-related subtypes and comprehensive analysis of characteristics of the tumor microenvironment infiltration in clear cell renal cell carcinoma.

Author

Zeng, Jiayi, Zhu, Ping, Tang, Yanlin, Zhang, Changzheng, Ye, Chujin, Cheng, Shouyu, Tian, Kaiwen, Yang, Bowen, Zeng, Weinan, Liu, Yanjun, Xian, Zhiyong, and Yu, Yuming

Subjects
*RENAL cell carcinoma, *APOPTOSIS, *TUMOR microenvironment, *PROGRAMMED cell death 1 receptors, *PYROPTOSIS, *PROGNOSTIC models
Abstract

Pyroptosis is a kind of programmed cell death triggered by the inflammasome. Growing evidence has revealed the crucial utility of pyroptosis in tumors. However, the potential mechanism of pyroptosis in clear cell renal cell carcinoma (ccRCC) is still unclear. In this research, we systematically analyze the genetic and transcriptional alterations of pyroptosis-related genes (PRGs) in ccRCC, identify pyroptosis-related subtypes, analyze the clinical and microenvironmental differences among different subtypes, develop a corresponding prognostic model to predict the prognosis of patients, and interpret the effect of pyroptosis on ccRCC microenvironment. This study provides a new perspective for a comprehensive understanding of the role of pyroptosis in ccRCC and its impact on the immune microenvironment, and a reliable scoring system was established to predict patients' prognosis. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

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