1. Oncogenic miR-425-5p is associated with cellular migration, proliferation and apoptosis in renal cell carcinoma
- Author
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Yawen Li, Fangting Zhang, Xionghui Wu, Canbin Lin, Zebo Chen, Xiang Pan, Lingzhi Tao, Liwen Zhao, Jing Quan, Liang Zhou, Yu Ding, Yulin Lai, Yongqing Lai, Jing Ye, Tao He, Liangchao Ni, Shuolei Sun, and Yimin Hu
- Subjects
0301 basic medicine ,Cancer Research ,renal cell carcinoma ,Oncogene ,microRNA ,Chemistry ,Cell ,Cell migration ,Articles ,Cell cycle ,microRNA-425-5p ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,medicine.anatomical_structure ,Oncology ,Downregulation and upregulation ,Cell culture ,Apoptosis ,oncogene ,030220 oncology & carcinogenesis ,medicine ,Cancer research ,Viability assay - Abstract
An increasing number of studies have demonstrated the function of microRNAs (miRNAs) in the initiation and development of various types of cancer. Among them, miR-425-5p is proven to serve an important function in several types of cancer, including gastric, cervical cancer, and hepatocellular carcinoma. However, the function of miR-425-5p in renal cell carcinoma (RCC) remains unclear. In the present study, it was demonstrated that the expression level of miR-425-5p was upregulated in RCC tissues and cell lines compared with normal tissues and cell lines (P
- Published
- 2018