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Your search keyword '"permeability pulmonary edema"' showing total 2 results
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2 results on '"permeability pulmonary edema"'

1. Increased Interleukin-8 in Epithelial Lining Fluid of Collapsed Lungs During One-Lung Ventilation for Thoracotomy.

Author

Komatsu, Yoshimichi, Yamamoto, Hiroshi, Tsushima, Kenji, Furuya, Shino, Yoshikawa, Sumiko, Yasuo, Masanori, Kubo, Keishi, Yamazaki, Yoshitaka, Hasegawa, Joh, Eguchi, Takashi, Kondo, Ryuichi, Yoshida, Kazuo, and Koizumi, Tomonobu

Subjects
*LUNG injury treatment, *THORACIC surgery, *INTERLEUKIN-8, *EPITHELIAL cells, *INFLAMMATION, *MOLECULAR probes, *ALBUMINS
Abstract

The present study was designed to evaluate inflammatory changes in collapsed lungs during one-lung ventilation using the assistance of a bronchoscopic microsampling probe. Serial albumin and interleukin (IL)-8 concentrations in epithelial lining fluid (ELF) were measured in seven patients undergoing resection of lung tumors. The samples were taken after induction of anesthesia (baseline), 30 min after one-lung ventilation was started (point 2), just before resuming two-lung ventilation (point 3), and 30 min after two-lung ventilation was restarted (point 4). The albumin and IL-8 concentrations in ELF were significantly increased at point 2 and point 3, respectively, and remained to be high, compared to the baseline. The increase in IL-8 at point 3 was correlated with the interval of one-lung ventilation; however, none developed specific acute lung injury. These findings suggest that inflammatory changes can occur on the epithelium of a collapsed lung even in patients who underwent successful and standard thoracic surgery. [ABSTRACT FROM AUTHOR]

Published
2012
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2. Increased Interleukin-8 in Epithelial Lining Fluid of Collapsed Lungs During One-Lung Ventilation for Thoracotomy

Author

Yoshitaka Yamazaki, Kazuo Yoshida, Tomonobu Koizumi, Joh Hasegawa, Hiroshi Yamamoto, Keishi Kubo, Shino Furuya, Masanori Yasuo, Ryuichi Kondo, Yoshimichi Komatsu, Kenji Tsushima, Sumiko Yoshikawa, and Takashi Eguchi

Subjects
Male, Pulmonary Atelectasis, medicine.medical_specialty, ARDS, Lung Neoplasms, medicine.medical_treatment, Interleukin-1beta, Immunology, Pulmonary Edema, Respiratory Mucosa, permeability pulmonary edema, re-expansion pulmonary edema, Lung injury, Collapsed Lung, Albumins, Humans, Immunology and Allergy, Medicine, Thoracotomy, Lung, Aged, Inflammation, bronchoscopic microsampling, Interleukin-6, Tumor Necrosis Factor-alpha, business.industry, Interleukin-8, Interleukin, Middle Aged, respiratory system, medicine.disease, thoracic surgery, One-Lung Ventilation, respiratory tract diseases, medicine.anatomical_structure, Cardiothoracic surgery, Anesthesia, Breathing, Female, business
Abstract

The present study was designed to evaluate inflammatory changes in collapsed lungs during one-lung ventilation using the assistance of a bronchoscopic microsampling probe. Serial albumin and interleukin (IL)-8 concentrations in epithelial lining fluid (ELF) were measured in seven patients undergoing resection of lung tumors. The samples were taken after induction of anesthesia (baseline), 30 min after one-lung ventilation was started (point 2), just before resuming two-lung ventilation (point 3), and 30 min after two-lung ventilation was restarted (point 4). The albumin and IL-8 concentrations in ELF were significantly increased at point 2 and point 3, respectively, and remained to be high, compared to the baseline. The increase in IL-8 at point 3 was correlated with the interval of one-lung ventilation; however, none developed specific acute lung injury. These findings suggest that inflammatory changes can occur on the epithelium of a collapsed lung even in patients who underwent successful and standard thoracic surgery., Article, INFLAMMATION. 35(6):1844-1850 (2012)

Published
2012
Full Text
View/download PDF

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