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1. [The potentiation of adjuvant arthritis in rats by vasopressin and its V2 agonist].

Author

Igonina NA, Evseev VA, and Kulikova OS

Subjects
Adoptive Transfer methods, Animals, Arthritis, Experimental immunology, Autoimmune Diseases immunology, Dose-Response Relationship, Drug, Drug Synergism, Epitopes drug effects, Epitopes immunology, Mice, Mice, Inbred C57BL, Rats, Rats, Wistar, T-Lymphocytes, Regulatory drug effects, T-Lymphocytes, Regulatory immunology, Arginine Vasopressin agonists, Arginine Vasopressin pharmacology, Arthritis, Experimental chemically induced, Autoimmune Diseases chemically induced, Deamino Arginine Vasopressin pharmacology
Abstract

Experiments on C57B1/6 mice and Wistar rats have demonstrated that neuropeptide vasopressin inhibits activity of antigen-specific suppressors and potentiates development of adjuvant arthritis. Vasopressin involvement in pathogenesis of autoimmunity is discussed.

Published
1999

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