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2. Elastin is an essential determinant of arterial morphogenesis.

Author

Li, Dean Y., Brooke, Benjamin, Davis, Elaine C., Mecham, Robert P., Sorensen, Lise K., Boak, Beth B., Eichwald, Ernst, and Keating, Mark T.

Subjects
ELASTIN, ARTERIES, ATHEROSCLEROSIS, ANIMAL models in research, CYTOCHEMISTRY
Abstract

Presents research which defined the role of elastin in arterial development and disease by generating mice that lack elastin. Previous thoughts about elastin's role; How the generated mice die; Developments similar to atherosclerosis; Traits of mice; Disruption of elastin and obstructive arterial disease; Elastin's regulatory function during arterial development.

Published
1998
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