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Objective: Recent advances in the field of biomedicine, specifically in the field of genomics, have led to an increase in the information available for conducting expression analysis. Expression analysis is a technique used in transcriptomics, a branch of genomics that deals with the study of messenger ribonucleic acid (mRNA) and the extraction of information contained in the genes. This increase in information is reflected in the exon arrays, which require the use of new techniques in order to extract the information. The purpose of this study is to provide a tool based on a mixture of experts model that allows the analysis of the information contained in the exon arrays, from which automatic classifications for decision support in diagnoses of leukemia patients can be made. The proposed model integrates several cooperative algorithms characterized for their efficiency for data processing, filtering, classification and knowledge extraction. The Cancer Institute of the University of Salamanca is making an effort to develop tools to automate the evaluation of data and to facilitate de analysis of information. This proposal is a step forward in this direction and the first step toward the development of a mixture of experts tool that integrates different cognitive and statistical approaches to deal with the analysis of exon arrays. The mixture of experts model presented within this work provides great capacities for learning and adaptation to the characteristics of the problem in consideration, using novel algorithms in each of the stages of the analysis process that can be easily configured and combined, and provides results that notably improve those provided by the existing methods for exon arrays analysis., Material and Methods: The material used consists of data from exon arrays provided by the Cancer Institute that contain samples from leukemia patients. The methodology used consists of a system based on a mixture of experts. Each one of the experts incorporates novel artificial intelligence techniques that improve the process of carrying out various tasks such as pre-processing, filtering, classification and extraction of knowledge. This article will detail the manner in which individual experts are combined so that together they generate a system capable of extracting knowledge, thus permitting patients to be classified in an automatic and efficient manner that is also comprehensible for medical personnel., Results and Conclusion: The system has been tested in a real setting and has been used for classifying patients who suffer from different forms of leukemia at various stages. Personnel from the Cancer Institute supervised and participated throughout the testing period. Preliminary results are promising, notably improving the results obtained with previously used tools. The medical staff from the Cancer Institute considers the tools that have been developed to be positive and very useful in a supporting capacity for carrying out their daily tasks. Additionally the mixture of experts supplies a tool for the extraction of necessary information in order to explain the associations that have been made in simple terms. That is, it permits the extraction of knowledge for each classification made and generalized in order to be used in subsequent classifications. This allows for a large amount of learning and adaptation within the proposed system.

Precision breeding techniques have been widely used to optimize expenses and increase livestock yields. Notwithstanding, the joint use of heterogeneous sensors and artificial intelligence techniques for the simultaneous analysis or detection of different problems that cattle may present has not been addressed. This study arises from the necessity to obtain a technological tool that faces this state of the art limitation. As novelty, this work presents a multi-agent architecture based on virtual organizations which allows to deploy a new embedded agent model in computationally limited autonomous sensors, making use of the Platform for Automatic coNstruction of orGanizations of intElligent Agents (PANGEA). To validate the proposed platform, different studies have been performed, where parameters specific to each animal are studied, such as physical activity, temperature, estrus cycle state and the moment in which the animal goes into labor. In addition, a set of applications that allow farmers to remotely monitor the livestock have been developed. [ABSTRACT FROM AUTHOR]

Among the most indispensable elements required by a city is electric power and the transmission towers used for its distribution. These towers have underground electrodes which must be reviewed on a regular basis by controlling different parameters to ensure that electrical resistance is in a secure range in order to avoid problems and risks. Using artificial intelligence, it is possible to ensure proper maintenance of the towers by estimating the required values and proposing a reduction in the size of the population sample, which will minimize the cost of operation. The use of an intelligent-agent virtual-organization based architecture is proposed within this working environment. By using mathematical estimation models and agreement based negotiations, the architecture is capable of maximizing estimations and minimizing associated costs. The proposed model has been evaluated with the developed software through a real case study, which permitted us to validate the proposed approach. [ABSTRACT FROM AUTHOR]

The lifespan of dental restorations is limited. Longevity depends on the material used and the different characteristics of the dental piece. However, it is not always the case that the best and longest lasting material is used since patients may prefer different treatments according to how noticeable the material is. Over the last 100 years, the most commonly used material has been silver amalgam, which, while very durable, is somewhat aesthetically displeasing. Our study is based on the collection of data from the charts, notes, and radiographic information of restorative treatments performed by Dr. Vera in 1993, the analysis of the information by computer artificial intelligence to determine the most appropriate restoration, and the monitoring of the evolution of the dental restoration. The data will be treated confidentially according to the Organic Law 15/1999 on 13 December on the Protection of Personal Data. This paper also presents a clustering technique capable of identifying the most significant cases with which to instantiate the case-base. In order to classify the cases, a mixture of experts is used which incorporates a Bayesian network and a multilayer perceptron; the combination of both classifiers is performed with a neural network. [ABSTRACT FROM AUTHOR]

Microarray technology can measure the expression levels of thousands of genes in an experiment. This fact makes the use of computational methods in cancer research absolutely essential. One of the possible applications is in the use of Artificial Intelligence techniques. Several of these techniques have been used to analyze expression arrays, but there is a growing need for new and effective solutions. This paper presents a Case-based reasoning (CBR) system for automatic classification of leukemia patients from microarray data. The system incorporates novel algorithms for data mining that allow filtering, classification, and knowledge extraction. The system has been tested and the results obtained are presented in this paper. [ABSTRACT FROM AUTHOR]

Abstract: The following article proposes the implementation of a system based on neural networks of CounterPropagation type and intelligent agents for analysis and assessment of the risk of flood caused by rain, in addition to the implementation of agents in mobile devices for the presentation of alerts. Because as is known, natural phenomena have always existed, but in recent years as a result of global warming we have seen that floods are becoming more frequent, which has forced the creation of specialized agencies and intelligent mechanisms to prevent the loss of human lives due to these phenomena. [Copyright &y& Elsevier]

Abstract: This paper presents a novel Ambient Intelligence based solution for shopping assistance. The core of the proposal is a CBR system developed for guiding and advising users in shopping areas. The CBR incorporates a neural based planner that identifies the most adequate plan for a given user based on user profile and interests. The RTPW neural network is based on the Kohonen one, and incorporates an interesting modification that allows a solution or a plan to be reached much more rapidly. Furthermore, once an initial plan has been reached, it is possible to identify alternatives by taking restrictions into account. The CBR system has been embedded within a deliberative agent and interacts with interface and commercial agents, which facilitate the construction of intelligent environments. This hybrid application, which works on execution time, has been tested and the results of the investigation and its evaluation in a shopping mall are presented within this paper. [Copyright &y& Elsevier]