1. A deep convolutional neural network for COVID-19 detection using chest X-rays
- Author
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Romis Attux and Pedro R. A. S. Bassi
- Subjects
FOS: Computer and information sciences ,Computer Science - Machine Learning ,COVID-19 detection ,Computer science ,Generalization ,LRP ,Output neuron keeping ,Computer Vision and Pattern Recognition (cs.CV) ,0206 medical engineering ,Computer Science - Computer Vision and Pattern Recognition ,Biomedical Engineering ,02 engineering and technology ,Convolutional neural network ,Machine Learning (cs.LG) ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,FOS: Electrical engineering, electronic engineering, information engineering ,Relevance (information retrieval) ,Twice transfer learning ,Interpretability ,Artificial neural network ,business.industry ,Image and Video Processing (eess.IV) ,Chest X-ray ,Process (computing) ,Pattern recognition ,Electrical Engineering and Systems Science - Image and Video Processing ,020601 biomedical engineering ,Path (graph theory) ,Original Article ,Artificial intelligence ,Transfer of learning ,business ,Neural networks - Abstract
Purpose We present image classifiers based on Dense Convolutional Networks and transfer learning to classify chest X-ray images according to three labels: COVID-19, pneumonia, and normal. Methods We fine-tuned neural networks pretrained on ImageNet and applied a twice transfer learning approach, using NIH ChestX-ray14 dataset as an intermediate step. We also suggested a novelty called output neuron keeping, which changes the twice transfer learning technique. In order to clarify the modus operandi of the models, we used Layer-wise Relevance Propagation (LRP) to generate heatmaps. Results We were able to reach test accuracy of 100% on our test dataset. Twice transfer learning and output neuron keeping showed promising results improving performances, mainly in the beginning of the training process. Although LRP revealed that words on the X-rays can influence the networks’ predictions, we discovered this had only a very small effect on accuracy. Conclusion Although clinical studies and larger datasets are still needed to further ensure good generalization, the state-of-the-art performances we achieved show that, with the help of artificial intelligence, chest X-rays can become a cheap and accurate auxiliary method for COVID-19 diagnosis. Heatmaps generated by LRP improve the interpretability of the deep neural networks and indicate an analytical path for future research on diagnosis. Twice transfer learning with output neuron keeping improved DNN performance.
- Published
- 2021
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